Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.53 |
| ▸ | DHODH | Q02127 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418954 | 0.90 | LMNA (0.48) | PTGDR2DHODHMEN1KMT2AMAPT | |
| SCHEMBL5397042 | 0.89 | KMT2A (0.58) | PTGDR2DHODHMEN1KMT2AMAPT | |
| SCHEMBL5415273 | 0.86 | PPARA (0.49) | PTGDR2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5398487 | 0.84 | PPARA (0.49) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5364912 | 0.82 | KMT2A (0.67) | PTGDR2DHODHMEN1KMT2AMAPT | |
| SCHEMBL5402842 | 0.81 | DHODH (0.62) | PTGDR2DHODHMEN1KMT2AMAPT | |
| SCHEMBL5412970 | 0.79 | PTGDR2 (0.62) | PTGDR2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5402536 | 0.79 | LMNA (0.55) | PTGDR2DHODHMEN1KMT2AMAPT | |
| SCHEMBL5369173 | 0.78 | KMT2A (0.59) | PTGDR2DHODHMEN1KMT2AMAPT | |
| SCHEMBL5403867 | 0.78 | LMNA (0.39) | DHODHMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |