Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186552 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| SCHEMBL8834093 | 0.76 | CYP1A2 (0.50) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| SCHEMBL9818808 | 0.72 | CYP2D6 (0.53) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| SCHEMBL6617339 | 0.67 | CYP2D6 (0.42) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| SCHEMBL1802065 | 0.65 | CYP3A4 (0.52) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| Perastine SCHEMBL1506306 | 0.65 | CYP3A4 (0.83) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| SCHEMBL16227209 | 0.65 | KCNA5 (1.00) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| SCHEMBL5267415 | 0.65 | CYP2D6 (0.68) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| SCHEMBL16226493 | 0.65 | KCNA5 (1.00) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| SCHEMBL16227210 | 0.65 | KCNA5 (1.00) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229729-B2 | Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method | KONICA MONOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-20050037274-A1 | Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2005-02-17 | — | — | US | disclosed |
| US-5622784-A | WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM | SEIKO EPSON CORPORATION (JP) | 1997-04-22 | — | — | US | disclosed |