Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405495 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12130576 | 0.76 | SLC6A3 (0.48) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10763685 | 0.76 | SLC6A4 (0.44) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 | |
| SCHEMBL10601133 | 0.76 | CYP1A2 (0.62) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9818808 | 0.76 | CYP2D6 (0.53) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL113896 | 0.76 | CYP1A2 (0.62) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10598753 | 0.74 | OPRM1 (0.63) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6619387 | 0.73 | CHRM2 (0.42) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6617339 | 0.72 | CYP2D6 (0.42) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL597049 | 0.71 | SIGMAR1 (0.49) | CYP2D6KCNH2SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446400-A4 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC NARA CO LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1446400-A1 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC Nara Co. Ltd. (KR) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003033489-A1 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC NARA CO., LTD. (KR) | 2003-04-24 | — | — | WO | disclosed |