Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 2/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.83 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.83 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.83 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.83 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.83 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.83 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.83 |
| ▸ | HTR1A | P08908 | 1/20 | 0.83 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.83 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.83 |
| ▸ | DRD1 | P21728 | 1/20 | 0.83 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.83 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.83 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.83 |
| ▸ | DRD3 | P35462 | 1/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perastine SCHEMBL29768269 | 0.98 | CYP3A4 (0.83) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL10357800 | 0.93 | SIGMAR1 (0.81) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| Cloperastine SCHEMBL29617329 | 0.91 | SLC6A2 (1.00) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| Cloperastine SCHEMBL9613613 | 0.91 | SLC6A2 (1.00) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL17942915 | 0.91 | CYP3A4 (0.75) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| Cloperastine SCHEMBL284715 | 0.91 | SLC6A2 (1.00) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| Cloperastine SCHEMBL23733 | 0.90 | CYP3A4 (1.00) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL1151981 | 0.89 | SLC6A2 (0.97) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| Cloperastine SCHEMBL1651228 | 0.89 | SLC6A2 (0.95) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL10357706 | 0.86 | SIGMAR1 (0.77) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-0259227-B1 | BENZHYDRYLOXYETHYL PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme: LES LABORATOIRES MERAM (FR) | 1991-12-27 | — | — | EP | claimed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | claimed |
| EP-0259227-A1 | Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-03-09 | — | — | EP | claimed |
| EP-4746966-A1 | 4-AMINO-2,6-BIS(PHENYLMETHYLENE)CYCLOHEXANONES AND THEIR USE | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025130120-A1 | USE OF MANGIFERIN IN PREPARING FERROPTOSIS INHIBITOR | 浙江省中医药研究院 | 2025-06-26 | — | — | WO | disclosed |
| CN-118806777-B | Application of stachyose in preparing medicine for preventing and relieving myocardial ischemia reperfusion injury | 无锡市第二人民医院 | 2025-03-18 | — | — | CN | disclosed |
| WO-2025021236-A1 | 4-AMINO-2,6-BIS(PHENYLMETHYLENE)CYCLOHEXANONES AND THEIR USE | Ustav Organicke Chemie A Biochemie AV CR v.v.i. (CZ) | 2025-01-30 | — | — | WO | disclosed |
| CN-118806777-A | Application of stachyose in preparing medicine for preventing and relieving myocardial ischemia reperfusion injury | 无锡市第二人民医院 | 2024-10-22 | — | — | CN | disclosed |
| CN-116270595-B | Application of biflavone compound in preparation of medicine for inhibiting neuronal cell iron death | 中国人民解放军军事科学院军事医学研究院 | 2024-09-27 | — | — | CN | disclosed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | disclosed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | disclosed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | disclosed |
| EP-0259227-A1 | Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-03-09 | — | — | EP | disclosed |
| EP-0259227-A1 | Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-03-09 | — | — | EP | disclosed |
| EP-0259227-A1 | Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-03-09 | — | — | EP | disclosed |