SCHEMBL5405672

SCHEMBL5405672

C=CC(=O)OCCc1cc(C(C)(C)CC(C)(C)C)c(O)c(C(C)(C)CC(C)(C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 3/20 0.45
▸ MET P08581 6/20 0.40
▸ TSHR P16473 5/20 0.40
▸ HPGD P15428 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ TP53 P04637 2/20 0.39
▸ HIF1A Q16665 2/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ THRB P10828 2/20 0.38
▸ ALOX5 P09917 2/20 0.34
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5412953 0.86 GAA (0.56) GAAMETTSHRHPGDALDH1A1
SCHEMBL11648518 0.86 THRB (0.49) GAATSHRHPGDALDH1A1TP53
SCHEMBL5405676 0.85 TSHR (0.46) GAAMETTSHRHPGDALDH1A1
SCHEMBL10651744 0.81 GAA (0.60) GAAMETTSHRHPGDALDH1A1
SCHEMBL15437699 0.80 GAA (0.59) GAATSHRHPGDALDH1A1TP53
SCHEMBL11794653 0.79 THRB (0.39) GAATSHRHPGDALDH1A1HIF1A
SCHEMBL11668133 0.77 GAA (0.55) GAATSHRHPGDALDH1A1TP53
SCHEMBL11654442 0.77 THRB (0.48) GAAMETTSHRHPGDALDH1A1
SCHEMBL2612492 0.76 GAA (0.51) GAATSHRALDH1A1TP53HIF1A
SCHEMBL22195129 0.76 TSHR (0.59) METTSHRHPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897312-B2 photoreceptors for electrophotography comprising undercoat layers, charge generation and charge transport layer on substrates; high resolution images KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-03-01 — — US disclosed
US-7229729-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MONOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-06-12 — — US disclosed
US-20050064309-A1 photoreceptors for electrophotography comprising undercoat layers, charge generation and charge transport layer on substrates; high resolution images KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. 2005-03-24 — — US disclosed
US-20050037274-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2005-02-17 — — US disclosed
US-6569586-B2 Comprises photosensitive layer and resin layer including organic polymer, siloxane component, and charge transfer component; durability KONICA CORPORATION (JP) 2003-05-27 — — US disclosed
US-20020076631-A1 Photoreceptor for forming electrostatic latent image KONICA CORPORATION (JP) 2002-06-20 — — US disclosed
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