SCHEMBL5405853

SCHEMBL5405853

CCC[C@@H](Cl)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL287797 1.00
SCHEMBL604353 1.00
SCHEMBL28276457 0.97 CHRM1 (0.52)
SCHEMBL29771413 0.97
Acetic Acid SCHEMBL11768608 0.95 CHRM1 (0.50)
SCHEMBL321177 0.84
SCHEMBL7820950 0.84
SCHEMBL7827885 0.84
SCHEMBL4252514 0.82 GPR84 (0.56)
Hydrochloric Acid SCHEMBL10662871 0.82 CA2 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-7183308-B1 Metod for the synthesis of perindopril and the pharmaceutically acceptable salts thereof LES LABORATOIRES SERVIER (FR) 2007-02-27 US disclosed
US-20070043103-A1 NOVEL METOD FOR THE SYNTHESIS OF PERINDOPRIL AND THE PHARMACEUTICALLY-ACCEPTABLE SALTS THEREOF LES LABORATOIRES SERVIER (FR) 2007-02-22 US disclosed
EP-1380590-B1 Method for synthesis of perindopril and its pharmaceutically acceptable salts SERVIER LAB (FR) 2006-09-06 EP disclosed
WO-2005023841-A1 NOVEL METHOD FOR THE SYNTHESIS OF PERINDOPRIL AND THE PHARMACEUTICALLY-ACCEPTABLE SALTS THEREOF LES LABORATOIRES SERVIER (FR) 2005-03-17 WO disclosed
EP-1380590-A1 Method for synthesis of perindopril and its pharmaceutically acceptable salts Les Laboratoires Servier (FR) 2004-01-14 EP disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed