Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694888 | 0.88 | TSHR (0.35) | METAP2METAP1CYP3A4TDP1 | |
| SCHEMBL7163809 | 0.87 | TDP1 (0.39) | CYP3A4TDP1ALDH1A1MAPK1 | |
| SCHEMBL951362 | 0.83 | METAP2 (0.35) | METAP2METAP1CYP3A4TDP1TP53 | |
| SCHEMBL19206327 | 0.82 | METAP2 (0.33) | METAP2METAP1 | |
| SCHEMBL19206364 | 0.81 | METAP2 (0.33) | METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL19206340 | 0.81 | METAP2 (0.33) | METAP2METAP1 | |
| SCHEMBL163845 | 0.80 | TDP1 (0.41) | CYP3A4TDP1TP53ACHEALDH1A1 | |
| SCHEMBL8735569 | 0.78 | CYP3A4 (0.36) | CYP3A4TDP1ALDH1A1MAPK1 | |
| SCHEMBL3997009 | 0.78 | TDP1 (0.39) | CYP3A4TDP1TP53ACHEALDH1A1 | |
| SCHEMBL3068169 | 0.78 | TDP1 (0.39) | CYP3A4TDP1TP53ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285607-B2 | Polymerisation of olefinic compounds | SASOL, CHEMICAL INDUSTRIES, LIMITED (ZA) | 2007-10-23 | — | — | US | claimed |
| US-20060020091-A1 | Polymerisation of olefinic compounds | SASOL CHEMICAL INDUSTRIES LIMITED (ZA) | 2006-01-26 | — | — | US | claimed |
| EP-3747942-A1 | BRIDGED PHOSPHORUS BASED FLAME RETARDANTS | EMPA Eidgenössische Materialprüfungs- und Forschungsanstalt (CH) | 2020-12-09 | — | — | EP | disclosed |
| US-7285607-B2 | Polymerisation of olefinic compounds | SASOL, CHEMICAL INDUSTRIES, LIMITED (ZA) | 2007-10-23 | — | — | US | disclosed |
| US-20060020091-A1 | Polymerisation of olefinic compounds | SASOL CHEMICAL INDUSTRIES LIMITED (ZA) | 2006-01-26 | — | — | US | disclosed |