Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405887 | 0.83 | METAP2 (0.35) | METAP2METAP1CYP3A4TDP1TP53 | |
| SCHEMBL301087 | 0.80 | CYP3A4 (0.41) | CYP3A4TDP1TP53ALDH1A1 | |
| SCHEMBL1241769 | 0.78 | CYP3A4 (0.39) | CYP3A4TDP1TP53ALDH1A1 | |
| SCHEMBL5694888 | 0.76 | TSHR (0.35) | METAP2METAP1CYP3A4TDP1HCAR3 | |
| SCHEMBL9403468 | 0.74 | CYP3A4 (0.36) | CYP3A4TDP1TP53 | |
| Dimethylamine SCHEMBL10849585 | 0.74 | CYP3A4 (0.36) | CYP3A4TDP1TP53 | |
| SCHEMBL11474282 | 0.72 | CES2 (0.37) | CYP3A4TDP1 | |
| SCHEMBL16351492 | 0.72 | MEN1 (0.33) | CYP3A4TDP1ALDH1A1 | |
| SCHEMBL6682714 | 0.71 | CYP3A4 (0.38) | CYP3A4TDP1TP53ALDH1A1 | |
| SCHEMBL49367 | 0.71 | TSHR (0.38) | CYP3A4TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456152-B1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | SASOL TECH PTY LTD (ZA) | 2012-06-13 | — | — | EP | claimed |
| JP-4308015-B2 | — | — | 2009-08-05 | — | — | JP | claimed |
| US-7300904-B2 | Trimerisation and oligomerisation of olefins using a chromium based catalyst | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2007-11-27 | — | — | US | claimed |
| JP-2005533872-A | — | — | 2005-11-10 | — | — | JP | claimed |
| US-20050131262-A1 | Trimerisation and oligomerisation of olefins using a chromium based catalyst | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2005-06-16 | — | — | US | claimed |
| EP-1456152-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | Sasol Technology (Pty) Ltd (ZA) | 2004-09-15 | — | — | EP | claimed |
| WO-2003053890-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | SASOL TECHNOLOGY (PTY) LTD (ZA) | 2003-07-03 | — | — | WO | claimed |
| EP-2287144-B1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2018-04-11 | — | — | EP | disclosed |
| EP-2287143-B1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2018-04-11 | — | — | EP | disclosed |
| US-20170044275-A9 | Methods of Preparation of an Olefin Oligomerization Catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2017-02-16 | — | — | US | disclosed |
| US-9550841-B2 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160251455-A1 | Methods of Preparation of an Olefin Oligomerization Catalyst | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2016-09-01 | — | — | US | disclosed |
| EP-1716089-B1 | METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-04-08 | — | — | EP | disclosed |
| EP-1716089-A1 | METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST | Chevron Phillips Chemical Company LP (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005082816-A1 | METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2005-09-09 | — | — | WO | disclosed |
| US-20050187391-A1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2005-08-25 | — | — | US | disclosed |
| US-20050187098-A1 | Methods of preparation of an olefin oligomerization catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY, LP | 2005-08-25 | — | — | US | disclosed |
| US-20050131262-A1 | Trimerisation and oligomerisation of olefins using a chromium based catalyst | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2005-06-16 | — | — | US | disclosed |
| EP-1456152-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | Sasol Technology (Pty) Ltd (ZA) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053890-A1 | TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST | SASOL TECHNOLOGY (PTY) LTD (ZA) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187391-A1 | Methods of preparation of an olefin oligomerization catalyst | ZRANB2, COG4, PPOX | METAP2 4476/4885METAP1 4688/4885CYP3A4 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.