Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.49 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 13/20 | 0.44 |
| ▸ | CTSK | P43235 | 12/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11889719 | 0.90 | CTSC (0.44) | CTSLCTSCCTSSCTSKCTSB | |
| SCHEMBL3873355 | 0.81 | CTSC (0.41) | CTSLCTSCCTSSCTSKCTSB | |
| SCHEMBL3870538 | 0.78 | CTSS (0.48) | CTSLCTSCCTSSCTSKCTSB | |
| SCHEMBL17493739 | 0.76 | CA1 (0.37) | CTSL | |
| SCHEMBL6020625 | 0.74 | CTSC (0.49) | CTSLCTSCCTSSCTSKCTSB | |
| SCHEMBL5407806 | 0.73 | CTSK (0.50) | CTSLCTSCCTSSCTSKCTSB | |
| SCHEMBL1146973 | 0.73 | SLC7A5 (0.44) | — | |
| SCHEMBL936382 | 0.73 | SLC7A5 (0.44) | — | |
| SCHEMBL19918392 | 0.73 | SLC7A5 (0.44) | — | |
| SCHEMBL2913071 | 0.73 | SLC7A5 (0.52) | CTSLCTSCCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007513890-A | — | — | 2007-05-31 | — | — | JP | claimed |
| EP-1694647-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2006-08-30 | — | — | EP | claimed |
| WO-2005056529-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2005-06-23 | — | — | WO | claimed |
| EP-1694647-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005056529-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2005-06-23 | — | — | WO | disclosed |