SCHEMBL5406017

SCHEMBL5406017

COc1ccc(OC)c(NC(=O)CC(C)=O)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.73
NPSR1 Q6W5P4 1/20 0.73
ALDH1A1 P00352 7/20 0.71
MEN1 O00255 3/20 0.71
GAA P10253 2/20 0.64
KDM4E B2RXH2 1/20 0.64
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
CYP2C9 P11712 1/20 0.64
MAPK1 P28482 1/20 0.64
CYP2C19 P33261 1/20 0.64
TP53 P04637 1/20 0.61
POLB P06746 3/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
RGS12 O14924 1/20 0.59
HPGD P15428 1/20 0.59
HTT P42858 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28020714 0.91 KMT2A (0.73) KMT2ANPSR1ALDH1A1MEN1GAA
SCHEMBL31570083 0.90 ALDH1A1 (0.66) KMT2ANPSR1ALDH1A1MEN1GAA
SCHEMBL17662314 0.88 KMT2A (0.73) KMT2ANPSR1ALDH1A1MEN1GAA
SCHEMBL4542785 0.88 ALDH1A1 (0.85) KMT2AALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL5807392 0.86 KMT2A (0.75) KMT2ANPSR1ALDH1A1MEN1GAA
SCHEMBL6594370 0.86 KMT2A (0.75) KMT2ANPSR1ALDH1A1MEN1GAA
SCHEMBL5807397 0.84 KMT2A (0.73) KMT2ANPSR1ALDH1A1MEN1GAA
SCHEMBL30420419 0.84 SMN1; SMN2 (0.72) KMT2AALDH1A1MEN1GAAPOLB
SCHEMBL20189628 0.84 KMT2A (0.73) KMT2ANPSR1ALDH1A1MEN1GAA
SCHEMBL3757797 0.84 KMT2A (0.73) KMT2ANPSR1ALDH1A1MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114195671-B Asymmetric malonyl aniline compound and synthesis method thereof 河南师范大学 2023-09-22 CN claimed
WO-2022228846-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-11-03 WO claimed
WO-2022117389-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-06-09 WO claimed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP claimed
CN-103183341-B Controllable synthesis method of N-doped graphitized carbon ball with hollow structures UNIV CHINA MINING 2015-04-29 CN claimed
CN-103183330-B Controllable synthesis method for nitrogen and phosphorus co-doped graphitized carbon ball with hollow structure UNIV CHINA MINING 2015-02-25 CN claimed
US-12421382-B2 Vehicle composition for inorganic fine particle dispersion, inorganic fine particle-dispersed slurry composition and method for producing inorganic fine particle-dispersed sheet SEKISUI CHEMICAL CO., LTD. (JP) 2025-09-23 US disclosed
WO-2025100475-A1 COMPOSITION FOR IMAGE RECORDING AND METHOD FOR PRODUCING SAME キヤノン株式会社 2025-05-15 WO disclosed
CN-114605764-B Carrier composition for inorganic microparticle dispersion, slurry composition for inorganic microparticle dispersion, and method for producing inorganic microparticle-dispersed sheet 积水化学工业株式会社 2024-01-19 CN disclosed
CN-114195671-B Asymmetric malonyl aniline compound and synthesis method thereof 河南师范大学 2023-09-22 CN disclosed
WO-2022228846-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-11-03 WO disclosed
CN-114605764-A Carrier composition for inorganic fine particle dispersion, inorganic fine particle dispersion slurry composition, and method for producing inorganic fine particle dispersible tablet 积水化学工业株式会社 2022-06-10 CN disclosed
WO-2022117389-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-06-09 WO disclosed
US-4169091-A Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component HOECHST AKTIENGESELLSCHAFT (DE) 1979-09-25 US disclosed
US-4103092-A Water-soluble quaternary ammonium non-heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1978-07-25 US disclosed
US-4075198-A PROCESS FOR MANUFACTURE OF BENZIDINE PIGMENTS COLOUR-CHEM LTD. (IN) 1978-02-21 US disclosed
US-4065500-A Water-soluble quaternary ammonium azo dyestuffs STERLING DRUG INC. (US) 1977-12-27 US disclosed
US-4024125-A Dis-azo pigments deriving from bis-diazotized diamino-2-phenyl-benzazolones HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 US disclosed
US-3991044-A Process for improving lightfastness of an azo pigment by heat treatment HERCULES INCORPORATED (US) 1976-11-09 US disclosed