Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 4/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20840178 | 0.88 | NPC1 (0.48) | SETDB1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL10204025 | 0.85 | SETDB1 (0.43) | SETDB1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL24269743 | 0.83 | NPC1 (0.48) | SETDB1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL29548392 | 0.83 | NPC1 (0.48) | SETDB1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4467278 | 0.83 | SETDB1 (0.57) | SETDB1MTNR1AMTNR1BKMT2AMAPT | |
| SCHEMBL6248360 | 0.82 | NPC1 (0.60) | SETDB1MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL4489127 | 0.81 | P2RX7 (0.54) | SETDB1MTNR1BP2RX7 | |
| SCHEMBL1991831 | 0.81 | SETDB1 (0.52) | SETDB1MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL10204843 | 0.81 | SETDB1 (0.47) | SETDB1MTNR1ANPC1RAB9AKMT2A | |
| SCHEMBL16318517 | 0.80 | SETDB1 (0.51) | SETDB1MTNR1AMTNR1BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980937-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-03-17 | — | — | US | claimed |
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-09-13 | — | — | US | claimed |
| EP-2463265-A2 | Process for the preparation of insecticidal aryl pyrrolidines | Bayer CropScience AG (DE) | 2012-06-13 | — | — | EP | claimed |
| US-20180098542-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| US-20180098542-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| US-9867375-B2 | Methods of pest control in soybean | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |
| US-9867375-B2 | Methods of pest control in soybean | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |
| US-20150237862-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-27 | — | — | US | disclosed |
| US-20150237862-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-27 | — | — | US | disclosed |
| US-20150208658-A1 | METHODS OF SOIL PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-30 | — | — | US | disclosed |
| US-20150208658-A1 | METHODS OF SOIL PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-30 | — | — | US | disclosed |
| US-8188122-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-8188122-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| EP-2148853-B1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-02-08 | — | — | EP | disclosed |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-04-07 | — | — | US | disclosed |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-04-07 | — | — | US | disclosed |
| CN-101663261-A | Insecticidal arylpyrrolidines | BAYER CROPSCIENCE AG | 2010-03-03 | — | — | CN | disclosed |
| EP-2148853-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008128711-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008128711-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | DDT, ITPR3, CYP51A1 | SETDB1 4420/4885MTNR1A 1345/4885MTNR1B 1016/4885 |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | DDT, ITPR3, CYP51A1 | SETDB1 4420/4885MTNR1A 1345/4885MTNR1B 1016/4885 |
| US-20180098542-A1 | METHODS OF PEST CONTROL IN SOYBEAN | BTF3, BRS3, CCNB3 | SETDB1 1793/4885MTNR1A 1074/4885MTNR1B 402/4885 |
| US-20150208658-A1 | METHODS OF SOIL PEST CONTROL | C1S, CBR3, CNPY3 | SETDB1 3336/4885MTNR1A 1351/4885MTNR1B 1290/4885 |
| US-20150237862-A1 | METHODS OF PEST CONTROL IN SOYBEAN | HRH4, HRH3, H1-3 | SETDB1 2064/4885MTNR1A 1012/4885MTNR1B 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.