Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23152448 | 0.86 | GAA (0.52) | GAAHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL756289 | 0.84 | SMN1; SMN2 (0.50) | GAAHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2968082 | 0.82 | SMN1; SMN2 (0.53) | GAAHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9184806 | 0.82 | GAA (0.48) | GAAHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL17186605 | 0.82 | GAA (0.44) | GAAHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1882976 | 0.82 | GAA (0.48) | GAAHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL23152464 | 0.80 | GAA (0.47) | GAAHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28492500 | 0.80 | F2 (0.46) | GAAHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6324391 | 0.80 | GAA (0.43) | GAAHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL23011371 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250492-B2 | Compositions and methods for inhibition of cancer invasion and angiogenesis | THE RESEARCH FOUNDATION AT STATE UNIVERSITY OF NEW YORK (US) | 2007-07-31 | — | — | US | disclosed |
| US-20070060528-A1 | ADMINISTRATION OF DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-15 | — | — | US | disclosed |
| US-20040115202-A1 | Compositions and methods for inhibition of cancer invasion and angiogenesis | THE RESEARCH FOUNDATION AT STATE UNIVERSITY OF NEW YORK | 2004-06-17 | — | — | US | disclosed |
| EP-1408908-A2 | COMPOSITIONS AND METHODS FOR INHIBITION OF CANCER INVASION AND ANGIOGENESIS | The Research Foundation of the State University of New York (US) | 2004-04-21 | — | — | EP | disclosed |
| US-6573096-B1 | Compositions and methods for inhibition of cancer invasion and angiogenesis | THE RESEARCH FOUNDATION AT STATE UNIVERSITY OF NEW YORK | 2003-06-03 | — | — | US | disclosed |
| US-20020132979-A1 | Compositions and methods for inhibition of cancer invasion and angiogenesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-09-19 | — | — | US | disclosed |
| WO-2001074299-A2 | COMPOSITIONS AND METHODS FOR INHIBITION OF CANCER INVASION AND ANGIOGENESIS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2001-10-11 | — | — | WO | disclosed |