Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22179999 | 0.98 | F2 (0.50) | F2GAAHTTSMN1; SMN2ALOX15 | |
| SCHEMBL3965980 | 0.85 | CA2 (0.46) | F2GAAPOLBCA2CHKA | |
| SCHEMBL5406500 | 0.80 | GAA (0.52) | GAAHTTSMN1; SMN2ALOX15ALDH1A1 | |
| SCHEMBL1882976 | 0.79 | GAA (0.48) | F2GAAHTTSMN1; SMN2ALOX15 | |
| SCHEMBL17186605 | 0.79 | GAA (0.44) | F2GAAHTTSMN1; SMN2ALOX15 | |
| SCHEMBL9184806 | 0.79 | GAA (0.48) | F2GAAHTTSMN1; SMN2ALOX15 | |
| SCHEMBL2950074 | 0.76 | F2 (0.50) | F2ALOX15ALDH1A1MAPT | |
| SCHEMBL2953468 | 0.74 | F2 (0.54) | F2ALDH1A1POLBCA2CHKA | |
| SCHEMBL12096425 | 0.74 | F2 (0.54) | F2ALDH1A1POLBCA2CHKA | |
| SCHEMBL45010 | 0.74 | F2 (0.54) | F2ALDH1A1POLBCA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848494-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-10-30 | — | — | CN | disclosed |