Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184806 | 1.00 | GAA (0.48) | GAAHTTALDH1A1F2SMN1; SMN2 | |
| SCHEMBL8468800 | 0.87 | — | — | |
| SCHEMBL22179999 | 0.82 | F2 (0.50) | GAAHTTALDH1A1F2SMN1; SMN2 | |
| SCHEMBL5406500 | 0.82 | GAA (0.52) | GAAHTTALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL28492500 | 0.79 | F2 (0.46) | GAAHTTALDH1A1F2SMN1; SMN2 | |
| SCHEMBL17336983 | 0.77 | F2 (0.50) | GAAHTTALDH1A1F2KMT2A | |
| SCHEMBL10723702 | 0.77 | CA2 (0.45) | KMT2AHSD11B1POLB | |
| SCHEMBL2968082 | 0.76 | SMN1; SMN2 (0.53) | GAAHTTALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL7700237 | 0.76 | GAA (0.44) | GAAHTTALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL23152448 | 0.75 | GAA (0.52) | GAAHTTALDH1A1SMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749448-B1 | USE OF PYRAZOLE-BLOCKED POLYISOCYANATES IN ONE-COMPONENT CLEAR COATINGS | ARCO CHEM TECH (US) | 2001-05-30 | — | — | EP | claimed |
| EP-0749448-A1 | ISOCYANATE-CROSSLINKED COATINGS HAVING REDUCED YELLOWING | OLIN CORPORATION (US) | 1996-12-27 | — | — | EP | claimed |
| EP-0749448-A4 | ISOCYANATE-CROSSLINKED COATINGS HAVING REDUCED YELLOWING | OLIN CORP (US) | 1996-06-19 | — | — | EP | claimed |
| WO-1995006674-A1 | ISOCYANATE-CROSSLINKED COATINGS HAVING REDUCED YELLOWING | OLIN CORPORATION (US) | 1995-03-09 | — | — | WO | claimed |
| CN-104781229-B | 1, 4-bis (isocyanatomethyl) cyclohexane, polyisocyanate composition, polyurethane resin, molded article, eyewear material, eyewear frame, and lens | 三井化学株式会社 | 2017-03-01 | — | — | CN | disclosed |
| CN-104136488-B | The compound of (methyl) acroleic acid esterification of radiation-hardenable | 湛新比利时股份有限公司 | 2016-07-13 | — | — | CN | disclosed |
| US-9360779-B2 | Electrophotographic photoconductor, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2016-06-07 | — | — | US | disclosed |
| US-20150241803-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2015-08-27 | — | — | US | disclosed |
| US-7937023-B2 | Method and a composition for producing an undercoat layer using dialkyl malonate blocked isocyanates (for electrophotographic applications) | EASTMAN KODAK COMPANY (US) | 2011-05-03 | — | — | US | disclosed |
| US-7196154-B2 | Method of producing polymer resins | LIGHT BLACK INC. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-20060009576-A1 | Method and a composition for producing an undercoat layer using dialkyl malonate blocked isocyanates (for electrophotographic applications) | EASTMAN KODAK COMPANY | 2006-01-12 | — | — | US | disclosed |
| US-20020166630-A1 | Method of producing polymer resins | LIGHT BLACK U.S.A., INC. | 2002-11-14 | — | — | US | disclosed |
| US-5969085-A | CONTAINING NONMESOGENIC LINEAR OLIGOESTER DIOL, HARDENER OF MESOGENIC POLYOL, CRYSTALLINE POLYOL OR MIXTURES, PHENOLIC ESTER ALCOHOL, CROSSLINKER | EXXON CHEMICAL PATENTS, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| US-5641854-A | NONMESOGENIC SUBSTANTIALLY LINEAR OLIGOESTER DIOL, HARDENER AND CROSSLINKER | EASTERN MICHIGAN UNIVERSITY (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0751978-A1 | POLYMERIC VEHICLE FOR HIGH SOLIDS COATINGS | EASTERN MICHIGAN UNIVERSITY (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1996023034-A1 | POLYMERIC VEHICLE FOR HIGH SOLIDS COATINGS | EASTERN MICHIGAN UNIVERSITY (US) | 1996-08-01 | — | — | WO | disclosed |
| WO-1995020004-A1 | POLYMERIC VEHICLE FOR HIGH SOLIDS COATINGS | EASTERN MICHIGAN UNIVERSITY (US) | 1995-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020166630-A1 | Method of producing polymer resins | PARG, PNMT, ALKBH5 | GAA 1278/4885HTT 474/4885ALDH1A1 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.