SCHEMBL5407760

SCHEMBL5407760

CC(C)N1SNc2ccccc2C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.51
RECQL P46063 1/20 0.51
CASP3 P42574 1/20 0.39
GRM4 Q14833 1/20 0.36
HPGD P15428 4/20 0.36
TDP1 Q9NUW8 3/20 0.35
POLB P06746 2/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
ALDH1A1 P00352 3/20 0.35
KLK7 P49862 1/20 0.35
MAP2K7 O14733 1/20 0.34
GMNN O75496 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bentazon SCHEMBL8539367 0.86 KDM4E (0.77) KDM4ERECQLCASP3GRM4
SCHEMBL11809766 0.84 KDM4E (0.43) KDM4ERECQLCASP3HPGDTDP1
SCHEMBL11381204 0.77 KDM4E (0.44) KDM4ERECQLCASP3HPGDTDP1
SCHEMBL11834820 0.72 KDM4E (0.41) KDM4ERECQLCASP3GRM4HPGD
SCHEMBL6447956 0.70 KDM4E (0.45) KDM4ERECQLCASP3HPGDGAA
Bentazon SCHEMBL29379785 0.68 KDM4E (1.00) KDM4ERECQLCASP3GRM4HPGD
Bentazon SCHEMBL53939 0.68 KDM4E (1.00) KDM4ERECQLCASP3GRM4HPGD
Bentazon SCHEMBL8878772 0.67 KDM4E (0.97) KDM4ERECQLCASP3GRM4HPGD
Bentazon SCHEMBL1150626 0.67 KDM4E (0.97) KDM4ERECQLCASP3GRM4HPGD
Bentazon SCHEMBL31261812 0.67 KDM4E (0.97) KDM4ERECQLCASP3GRM4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2836072-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT Dongbu Farm Hannong Co., Ltd. (KR) 2015-02-18 EP claimed
CN-104320972-A Herbicidal composition comprising uracil compound as active ingredient DONGBU FARM HANNONG CO LTD 2015-01-28 CN claimed
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2015-01-22 US claimed
WO-2013154396-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2013-10-17 WO claimed
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2005-09-01 US claimed
US-20050090397-A1 Herbicides made from substituted aryl ketones BAYER CROPSCIENCE AG (GB) 2005-04-28 US claimed
US-6849578-B1 Selective herbicides based on 2,6-disubstituted pyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2005-02-01 US claimed
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US claimed
US-20040116294-A1 Herbicides based on substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2004-06-17 US claimed
EP-1423009-A2 HERBICIDES MADE FROM SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-06-02 EP claimed
EP-0639050-B1 SYNERGISTIC COMPOSITION AND PROCESS FOR SELECTIVE WEED CONTROL NOVARTIS AG (CH) 2000-12-27 EP claimed
EP-0929221-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AG (DE) 1999-07-21 EP claimed
US-5858920-A SYNERGISTIC MIXTURE; PLANT SAFENING AGENT BAYER AKTIENGESELLSCHAFT (DE) 1999-01-12 US claimed
WO-1998012923-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-02 WO claimed
EP-0645964-B1 HERBICIDAL COMPOSITION DOWELANCO (US) 1996-10-09 EP claimed
EP-0330904-B1 Herbicidal agent in the form of aqueous microemulsions HOECHST AG (DE) 1994-04-20 EP claimed
EP-0232067-B2 Substituted pyridinesulfonamide compounds, herbicidal composition containing them, and method of preparing these compounds ISHIHARA SANGYO KAISHA (JP) 1994-03-16 EP claimed
US-5070197-A WATER-SOLUBLE PESTICIDES; ONE STEP; CONTINUOUS PROCESSING UNIROYAL CHEMICAL COMPANY, INC. (US) 1991-12-03 US claimed
EP-0004414-B1 MIXTURES OF HERBICIDAL PYRIDYLOXYPHENOXYPROPANOIC ACID DERIVATIVES WITH OTHER HERBICIDES, AND PROCESSES OF KILLING UNWANTED PLANTS THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-07-24 EP claimed
EP-0027915-B1 HERBICIDAL AGENTS BASED ON DIPHENYL ETHERS AND BENZOTHIADIAZINONE DIOXIDES OR PYRIDINOTHIADIAZINONE DIOXIDES, AND THEIR USE BASF Aktiengesellschaft (DE) 1983-05-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones DDT, CBR3, CYP1B1 KDM4E 1246/4885RECQL 783/4885CASP3 383/4885
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT UNG, DDT, HDHD5 KDM4E 1146/4885RECQL 510/4885CASP3 534/4885
US-20050090397-A1 Herbicides made from substituted aryl ketones DDT, CBR3, CBR1 KDM4E 969/4885RECQL 437/4885CASP3 574/4885
US-20040171488-A1 N-aryl-uracils based Herbicides DDT, UNG, DDC KDM4E 874/4885RECQL 846/4885CASP3 733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.