SCHEMBL540784

SCHEMBL540784

CCCC(O)c1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
MAPT P10636 1/20 0.42
LMNA P02545 2/20 0.41
RIPK1 Q13546 1/20 0.39
CHRNA7 P36544 1/20 0.38
CA12 O43570 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
SLC6A3 Q01959 3/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
ACHE P22303 1/20 0.37
ALOX5 P09917 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
TSHR P16473 1/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21633858 0.91 LMNA (0.48) ALDH1A1LMNARIPK1ESR1ESR2
SCHEMBL1773587 0.89 HRH3 (0.46) ALDH1A1MAPTLMNARIPK1SLC6A4
SCHEMBL6207044 0.87 S1PR2 (0.46) ALDH1A1MAPTCA2SLC6A4HRH3
SCHEMBL14717561 0.85 S1PR2 (0.48) CA2SLC6A4HRH3
SCHEMBL2084176 0.85 S1PR2 (0.48) CA2SLC6A4HRH3
SCHEMBL12420337 0.85 S1PR2 (0.48) CA2SLC6A4HRH3
SCHEMBL29861491 0.84 LMNA (0.43) ALDH1A1LMNARIPK1ESR1ESR2
SCHEMBL3176056 0.82 ALDH1A1 (0.42) ALDH1A1MAPTLMNARIPK1CHRNA7
SCHEMBL6055300 0.82 LMNA (0.41) ALDH1A1LMNARIPK1ESR1ESR2
SCHEMBL1917704 0.82 TAAR1 (0.56) ALDH1A1MAPTLMNASLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1647262-B2 Anhydrous cosmetic composition comprising electrophilic monomers and acid, and use for cosmetic treatment of hair OREAL (FR) 2012-02-08 EP claimed
EP-1455738-B1 USE OF ELECTROPHILIC MONOMERS FOR HAIR TREATMENT OREAL (FR) 2010-07-28 EP claimed
EP-1647262-B1 Anhydrous cosmetic composition comprising electrophilic monomers and acid, and use for cosmetic treatment of hair OREAL (FR) 2009-08-05 EP claimed
EP-1847252-A2 Composition comprising a cyanoacrylate monomer, a glucidic compound and a liquid organic solvent and cosmetic treatment methods L'Oréal (FR) 2007-10-24 EP claimed
EP-1844818-A2 Water-in-oil emulsion for the treatment of keratin fibres, comprising a cyanoacrylate monomer L'OREAL (FR) 2007-10-17 EP claimed
EP-1844817-A2 Water-in-oil emulsion for the treatment of keratin fibres, comprising a cyanoacrylate monomer and ammonia L'OREAL (FR) 2007-10-17 EP claimed
EP-1787680-A2 Cosmetic composition based on electrophilic monomers and a dispersion of surface-stabilised polymer particles L'Oréal (FR) 2007-05-23 EP claimed
EP-1707241-A1 Composition comprising an electrophilic monomer and an amino acid which is different from cystein and cosmetic treatment L'OREAL (FR) 2006-10-04 EP claimed
EP-1707186-A1 Composition comprising an electrophile monomer and a conductive polymer and processes of keratinic fiber cosmetic treatments L'OREAL (FR) 2006-10-04 EP claimed
EP-1649894-A2 Composition comprising electrophilic monomers and organic salts, use for treatment of keratinic materials L'OREAL (FR) 2006-04-26 EP claimed
EP-1647260-A1 use for cosmetic treatment of keratinic material of a composition comprising an electrophilic monomer and a non-siloxane polymer, thereby achieving a soft coating L'OREAL (FR) 2006-04-19 EP claimed
EP-1647264-A1 use for cosmetic treatment of keratinic material of a composition comprising an electrophilic monomer and a non-siloxane polymer, thereby achieving a rigid coating L'OREAL (FR) 2006-04-19 EP claimed
EP-1647265-A1 Use for the cosmetic treatment of keratinous material of non sticky compositions based on electrophilic monomeres and non-silicon polymers L'OREAL (FR) 2006-04-19 EP claimed
EP-1647259-A1 use for treatment of keratinic materials of compositions comprising electrophilic monomers and agents forming liquid crystals L'OREAL (FR) 2006-04-19 EP claimed
EP-1647308-A1 Use of a composition baded on electrophilic monomers and micro- or nano-particles L'OREAL (FR) 2006-04-19 EP claimed
EP-1647258-A1 Hair care composition based on electrophilic monomers and lubricating solid micro or nano particles L'OREAL (FR) 2006-04-19 EP claimed
EP-1647263-A1 Double chamber aerosol device comprising electrophilic monomers and use for the cosmetic treatment of hair L'OREAL (FR) 2006-04-19 EP claimed
EP-1647262-A1 Anhyrous cosmetic composition comprising electrophilic monomers and acid, and use for cosmetic treatment of hair L'OREAL (FR) 2006-04-19 EP claimed
EP-1455738-A2 USE OF ELECTROPHILIC MONOMERS FOR HAIR TREATMENT L'OREAL (FR) 2004-09-15 EP claimed
WO-2003053380-A2 USE OF ELECTROPHILIC MONOMERS FOR HAIR TREATMENT L'OREAL (FR) 2003-07-03 WO claimed