Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CTSH | P09668 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598550 | 0.89 | ACE (0.48) | CTSCCYP1A2CYP3A4CTSHCYP2D6 | |
| SCHEMBL27788518 | 0.87 | CTSC (0.57) | CTSCCYP1A2CYP3A4CTSHCYP2D6 | |
| SCHEMBL2184166 | 0.85 | CTSC (0.59) | CTSCCYP1A2CYP3A4CTSHCYP2D6 | |
| SCHEMBL6805537 | 0.85 | CTSC (0.59) | CTSCCYP1A2CYP3A4CTSHCYP2D6 | |
| SCHEMBL2269225 | 0.77 | ACACB (0.58) | CTSCACACBSLC6A2SLC6A3 | |
| SCHEMBL28445731 | 0.76 | CTSD (0.46) | CTSKMMEACECPA1ACE2 | |
| SCHEMBL8164760 | 0.76 | CYP2C9 (0.53) | HTTDPP7LMNAKMT2AEPHX2 | |
| SCHEMBL4747248 | 0.76 | CYP2C9 (0.53) | HTTDPP7LMNAKMT2AEPHX2 | |
| SCHEMBL5153995 | 0.75 | ACE (0.48) | CTSCSLC6A2PLGMMEACE | |
| SCHEMBL5323913 | 0.75 | CTSC (0.55) | CTSCCYP1A2CYP3A4CTSHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169888-B2 | Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2007-01-30 | — | — | US | claimed |