SCHEMBL5407964

SCHEMBL5407964

CC(C)N(C(P(=O)(O)O)P(=O)(O)O)C(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.46
ANPEP P15144 4/20 0.39
LAP3 P28838 4/20 0.39
ERAP1 Q9NZ08 1/20 0.39
CA2 P00918 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
MMP1 P03956 1/20 0.31
MMP8 P22894 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61410 0.81 FDPS (0.48) FDPSANPEPLAP3ERAP1CA2
SCHEMBL11589305 0.80 FDPS (0.44) FDPSANPEPLAP3ERAP1CA2
Ammonia Solution, Strong SCHEMBL7596444 0.78 FDPS (0.46) FDPSANPEPLAP3ERAP1
Ammonia Solution, Strong SCHEMBL10538038 0.78 FDPS (0.46) FDPSANPEPLAP3ERAP1
Ammonia Solution, Strong SCHEMBL10863732 0.78 FDPS (0.46) FDPSANPEPLAP3ERAP1
SCHEMBL1557620 0.74 FDPS (0.39) FDPSANPEPLAP3ERAP1
SCHEMBL3615575 0.72 FDPS (0.43) FDPSANPEPLAP3ERAP1ALDH1A1
SCHEMBL8620092 0.72 ANPEP (0.41) FDPSANPEPLAP3ERAP1ALDH1A1
Sulfuric Acid SCHEMBL6259443 0.72 FDPS (0.37) FDPSANPEPLAP3ERAP1
Hypophosphorous Acid SCHEMBL8052568 0.71 FDPS (0.40) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7294733-B2 Method for preparing formylphosphonic acid MONSANTO TECHNOLOGY LLC (US) 2007-11-13 US disclosed
US-20060211881-A1 METHOD FOR PREPARING FORMYLPHOSPHONIC ACID MONSANTO TECHNOLOGY LLC (US) 2006-09-21 US disclosed
US-6762317-B2 AMINOMETHYLPHOSPHONIC ACID IS CONTACTED WITH WATER, AN ALCOHOL, A PHENOL AND AN OXIDIZING GAS IN THE PRESENCE OF A CATALYST MONSANTO COMPANY 2004-07-13 US disclosed
US-20030114706-A1 Method for preparing formylphosphonic acid FRANCZYK THADDEUS S (US) 2003-06-19 US disclosed
US-20010031889-A1 Method for preparing formylphosphonic acid FRANCZYK THADDEUS S (US) 2001-10-18 US disclosed
US-6274760-B1 CATALYTIC DECOMPOSITION OF (PHOSPHONOMETHYL)AMINE OXIDE MONSANTO CO. 2001-08-14 US disclosed
US-6218570-B1 CONTACTING AMINOMETHYLPHOSPHONIC ACID WITH WATER, ALCOHOL OR PHENOL; CATALYTIC OXIDATION WITH GAS; FORMYLATION MONSANTO COMPANY 2001-04-17 US disclosed
US-6054608-A REACTING AMINOMETHYLPHOSPHONATE WITH WATER OR ALCOHOL OR PHENOL DERIVATIVE IN PRESENCE OF CATALYST AND OXIDIZING GAS TO FORM FORMYLPHOSPHONIC ACID MONSANTO COMPANY (US) 2000-04-25 US disclosed
WO-2000009519-A1 PREPARATION OF FORMYLPHOSPHONIC ACID FROM (PHOSPHONOMETHYL)AMINE N-OXIDES MONSANTO COMPANY (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031889-A1 Method for preparing formylphosphonic acid PHOSPHO1, PNPO, MPHOSPH6 FDPS 17/4885ANPEP 827/4885LAP3 1697/4885
US-20030114706-A1 Method for preparing formylphosphonic acid PHOSPHO1, PNPO, MPHOSPH6 FDPS 17/4885ANPEP 827/4885LAP3 1697/4885
US-20060211881-A1 METHOD FOR PREPARING FORMYLPHOSPHONIC ACID PHOSPHO1, PNPO, MPHOSPH6 FDPS 17/4885ANPEP 827/4885LAP3 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.