⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732 | 0.98 | — | — | |
| SCHEMBL16913025 | 0.97 | — | — | |
| SCHEMBL2681012 | 0.97 | — | — | |
| SCHEMBL332957 | 0.97 | — | — | |
| Water SCHEMBL30891750 | 0.95 | — | — | |
| Glycerin SCHEMBL17353367 | 0.87 | — | — | |
| SCHEMBL11455191 | 0.72 | TDP1 (0.31) | — | |
| SCHEMBL6645893 | 0.70 | — | — | |
| SCHEMBL11452979 | 0.67 | — | — | |
| SCHEMBL30893667 | 0.63 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112274513-B | Pharmaceutical composition containing pyrroloquinoline quinone trilithium salt nonahydrate, capsule and preparation method of capsule | 上海日馨生物科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-112274513-A | Pharmaceutical composition containing pyrroloquinoline quinone trilithium salt nonahydrate, capsule and preparation method of capsule | 上海日馨生物科技有限公司 | 2021-01-29 | — | — | CN | claimed |
| US-9738639-B2 | Pyrroloquinoline quinone lithium salt crystal and preparation method and application thereof | SHANGHAI RI XIN BIOTECHNOLOGY CO., LTD. (CN) | 2017-08-22 | — | — | US | claimed |
| US-20160137641-A1 | PYRROLOQUINOLINE QUINONE LITHIUM SALT CRYSTAL AND PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI RAISING PHARMACEUTICAL CO., LTD. (CN) | 2016-05-19 | — | — | US | claimed |
| EP-2998305-A1 | PYRROLOQUINOLINE QUINONE LITHIUM SALT CRYSTAL AND PREPARATION METHOD AND APPLICATION THEREOF | Shanghai Ri Xin Biotechnology Co. Ltd. (CN) | 2016-03-23 | — | — | EP | claimed |
| CN-112274513-B | Pharmaceutical composition containing pyrroloquinoline quinone trilithium salt nonahydrate, capsule and preparation method of capsule | 上海日馨生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112274513-B | Pharmaceutical composition containing pyrroloquinoline quinone trilithium salt nonahydrate, capsule and preparation method of capsule | 上海日馨生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112274513-A | Pharmaceutical composition containing pyrroloquinoline quinone trilithium salt nonahydrate, capsule and preparation method of capsule | 上海日馨生物科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112274513-A | Pharmaceutical composition containing pyrroloquinoline quinone trilithium salt nonahydrate, capsule and preparation method of capsule | 上海日馨生物科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| US-9738639-B2 | Pyrroloquinoline quinone lithium salt crystal and preparation method and application thereof | SHANGHAI RI XIN BIOTECHNOLOGY CO., LTD. (CN) | 2017-08-22 | — | — | US | disclosed |
| US-9738639-B2 | Pyrroloquinoline quinone lithium salt crystal and preparation method and application thereof | SHANGHAI RI XIN BIOTECHNOLOGY CO., LTD. (CN) | 2017-08-22 | — | — | US | disclosed |
| US-20160137641-A1 | PYRROLOQUINOLINE QUINONE LITHIUM SALT CRYSTAL AND PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI RAISING PHARMACEUTICAL CO., LTD. (CN) | 2016-05-19 | — | — | US | disclosed |
| US-20160137641-A1 | PYRROLOQUINOLINE QUINONE LITHIUM SALT CRYSTAL AND PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI RAISING PHARMACEUTICAL CO., LTD. (CN) | 2016-05-19 | — | — | US | disclosed |
| EP-2998305-A1 | PYRROLOQUINOLINE QUINONE LITHIUM SALT CRYSTAL AND PREPARATION METHOD AND APPLICATION THEREOF | Shanghai Ri Xin Biotechnology Co. Ltd. (CN) | 2016-03-23 | — | — | EP | disclosed |
| EP-2998305-A1 | PYRROLOQUINOLINE QUINONE LITHIUM SALT CRYSTAL AND PREPARATION METHOD AND APPLICATION THEREOF | Shanghai Ri Xin Biotechnology Co. Ltd. (CN) | 2016-03-23 | — | — | EP | disclosed |
| WO-2015000370-A1 | PYRROLOQUINOLINE QUINONE LITHIUM SALT CRYSTAL AND PREPARATION METHOD AND APPLICATION THEREOF | 上海日馨生物科技有限公司 (CN) | 2015-01-08 | — | — | WO | disclosed |
| EP-2415770-A1 | LITHIUM DERIVATIVES OF PYRROLOQUINOLINE QUINONE AND PREPARATION METHOD THEREOF | Shanghai Rixin Bio-techonology Co., Ltd. (CN) | 2012-02-08 | — | — | EP | disclosed |
| US-20110313164-A1 | LITHIUM DERIVATIVES OF PYRROLOQUINOLINE QUINONE AND PREPARATION METHOD THEREOF | SHANGHAI RIXIN BIO-TECHNOLOGY CO., LTD. (CN) | 2011-12-22 | — | — | US | disclosed |