Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.64 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | PDE5A | O76074 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19523723 | 0.98 | ALDH1A1 (0.62) | CSNK2A2CSNK2BCSNK2A1RXFP1MEN1 | |
| SCHEMBL1604847 | 0.85 | CSNK2A2 (0.67) | CSNK2A2CSNK2BCSNK2A1MEN1PTGS2 | |
| SCHEMBL13164925 | 0.84 | CSNK2A2 (0.63) | CSNK2A2CSNK2BCSNK2A1MEN1PTGS2 | |
| SCHEMBL13164903 | 0.78 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1RXFP1MEN1 | |
| SCHEMBL13164894 | 0.78 | MAPT (0.84) | CSNK2A2CSNK2BCSNK2A1MEN1PTGS2 | |
| SCHEMBL10237224 | 0.77 | MAPT (0.68) | CSNK2A2CSNK2BCSNK2A1MEN1PTGS2 | |
| SCHEMBL13164898 | 0.77 | MEN1 (0.98) | CSNK2A2CSNK2BCSNK2A1RXFP1MEN1 | |
| SCHEMBL759362 | 0.76 | LMNA (0.63) | CSNK2A2CSNK2BCSNK2A1MEN1PTGS2 | |
| SCHEMBL14623890 | 0.76 | CSNK2A2 (0.65) | CSNK2A2CSNK2BCSNK2A1MEN1PTGS2 | |
| SCHEMBL13164924 | 0.76 | PDE5A (0.61) | CSNK2A2CSNK2BCSNK2A1MEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413696-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | Mount Sinai School Of Medicine Of New York University (US) | 2012-02-08 | — | — | EP | claimed |
| WO-2010114636-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2010-10-07 | — | — | WO | claimed |
| EP-2413696-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | Mount Sinai School Of Medicine Of New York University (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114636-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010114636-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2010-10-07 | — | — | WO | disclosed |