Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668252 | 0.91 | LMNA (0.66) | TP53LMNASMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL28879087 | 0.89 | LMNA (0.67) | TP53LMNASMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL28879019 | 0.89 | LMNA (0.67) | TP53LMNASMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL28878994 | 0.89 | LMNA (0.67) | TP53LMNASMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL28716632 | 0.89 | LMNA (0.67) | TP53LMNASMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL29968953 | 0.89 | LMNA (0.67) | TP53LMNASMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL29968482 | 0.89 | LMNA (0.67) | TP53LMNASMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL28860662 | 0.89 | LMNA (0.67) | TP53LMNASMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL9422768 | 0.88 | KDM4E (0.67) | TP53LMNASMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL2361056 | 0.87 | TP53 (0.69) | TP53LMNASMN1; SMN2RECQLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044033-B1 | A REGIOSELECTIVE PALLADIUM CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI SA (FR) | 2012-02-08 | — | — | EP | claimed |