Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031900 | 0.86 | ESR1 (0.43) | L3MBTL1SCN9A | |
| SCHEMBL4029614 | 0.81 | ESR1 (0.39) | L3MBTL1SCN9A | |
| SCHEMBL4031930 | 0.80 | SCN9A (0.45) | L3MBTL1SCN9A | |
| SCHEMBL5404922 | 0.79 | ALDH1A1 (0.51) | L3MBTL1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11888544 | 0.77 | PTGER1 (0.49) | L3MBTL1KHKKDM4EALDH1A1SCN9A | |
| SCHEMBL4034001 | 0.77 | L3MBTL1 (0.59) | L3MBTL1KHKKDM4EALDH1A1TDP1 | |
| SCHEMBL11688645 | 0.76 | L3MBTL1 (0.55) | L3MBTL1KHKKDM4EALDH1A1RECQL | |
| SCHEMBL13106278 | 0.74 | ADORA2A (0.60) | MAPTADORA2A | |
| SCHEMBL17306877 | 0.73 | L3MBTL1 (0.51) | L3MBTL1KHKKDM4EALDH1A1SCN9A | |
| SCHEMBL822675 | 0.72 | L3MBTL1 (0.56) | L3MBTL1KHKKDM4EALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241791-B2 | Substituted 4-(indazol-3-yl)phenols | WYETH (US) | 2007-07-10 | — | — | US | disclosed |