Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.63 |
| ▸ | PPARG | P37231 | 14/20 | 0.63 |
| ▸ | PPARD | Q03181 | 12/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365330 | 0.90 | PPARG (0.53) | PPARAPPARGPPARD | |
| SCHEMBL5365342 | 0.83 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL6575581 | 0.82 | PPARG (0.45) | PPARAPPARGPPARD | |
| SCHEMBL5375683 | 0.82 | PPARG (0.45) | PPARAPPARGPPARD | |
| SCHEMBL4652349 | 0.80 | CXCR2 (0.50) | PPARAPPARGPPARD | |
| SCHEMBL6055973 | 0.80 | PPARA (0.73) | PPARAPPARGPPARD | |
| SCHEMBL4455247 | 0.80 | PPARA (0.73) | PPARAPPARGPPARD | |
| SCHEMBL4460245 | 0.79 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL4460251 | 0.79 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL7617610 | 0.79 | PPARA (0.72) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241923-B2 | Phenylalkyloxy-phenyl derivatives | ASTRAZENECA AB (SE) | 2007-07-10 | — | — | US | disclosed |
| EP-1638926-A1 | 2-ETHOXY-3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF LIPID DISORDERS | Astrazeneca AB (SE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113276-A1 | 2-ETHOXY-3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF LIPID DISORDERS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | disclosed |
| US-20040176444-A1 | Phenylalkyloxy-phenyl derivatives | ASTRAZENECA AB (SE) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176444-A1 | Phenylalkyloxy-phenyl derivatives | GPR119, IAPP, INSR | PPARA 87/4885PPARG 53/4885PPARD 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.