⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7579230 | 0.75 | — | — | |
| SCHEMBL491268 | 0.73 | — | — | |
| SCHEMBL20856300 | 0.71 | — | — | |
| SCHEMBL1243288 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL8520336 | 0.71 | — | — | |
| SCHEMBL28035801 | 0.71 | — | — | |
| SCHEMBL3238308 | 0.69 | — | — | |
| Sulfuric Acid SCHEMBL27425398 | 0.67 | TDP1 (0.33) | — | |
| SCHEMBL4835244 | 0.67 | — | — | |
| SCHEMBL11876572 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265136-B1 | Substituted stilbene compounds with vascular damaging activity | ANGIOGENE PHARMACEUTICALS LTD. (GB) | 2007-09-04 | — | — | US | disclosed |
| EP-1154767-B9 | SUBSTITUTED STILBENE COMPOUNDS WITH VASCULAR DAMAGING ACTIVITY | ANGIOGENE PHARM LTD (GB) | 2006-06-28 | — | — | EP | disclosed |
| EP-1154767-B1 | SUBSTITUTED STILBENE COMPOUNDS WITH VASCULAR DAMAGING ACTIVITY | ANGIOGENE PHARM LTD (GB) | 2006-02-15 | — | — | EP | disclosed |
| EP-1154767-A1 | SUBSTITUTED STILBENE COMPOUNDS WITH VASCULAR DAMAGING ACTIVITY | Angiogene Pharmaceuticals Ltd (GB) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000048590-A1 | SUBSTITUTED STILBENE COMPOUNDS WITH VASCULAR DAMAGING ACTIVITY | ANGIOGENE PHARMACEUTICALS LTD. (GB) | 2000-08-24 | — | — | WO | disclosed |