⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835244 | 0.71 | — | — | |
| SCHEMBL5409448 | 0.69 | — | — | |
| SCHEMBL4881549 | 0.69 | — | — | |
| SCHEMBL1652638 | 0.69 | — | — | |
| SCHEMBL20084619 | 0.69 | — | — | |
| SCHEMBL253091 | 0.69 | — | — | |
| SCHEMBL8718732 | 0.67 | CA1 (0.31) | — | |
| SCHEMBL708131 | 0.67 | CA5A (0.35) | — | |
| SCHEMBL27655452 | 0.65 | — | — | |
| SCHEMBL2051479 | 0.64 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106916138-B | A kind of synthetic method of methane-disulfonic acid methylene ester | 山东永浩新材料科技有限公司 | 2019-04-09 | — | — | CN | disclosed |
| CN-106916138-A | A kind of synthetic method of methane-disulfonic acid methylene ester | 山东永浩新材料科技有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103755679-A | Alkylene disulfonic anhydride preparation method | NINGDE AMPEREX TECHNOLOGY LTD | 2014-04-30 | — | — | CN | disclosed |
| CN-102464649-A | Synthesis of methylene methanedisulfonate by ball milling method | FUJIAN MATTER STRUCTURE | 2012-05-23 | — | — | CN | disclosed |
| CN-102464648-A | Refining and purifying method of methylene methanedisulfonate | FUJIAN MATTER STRUCTURE | 2012-05-23 | — | — | CN | disclosed |
| US-7803832-B2 | N-(1-arylpyrazol-4L)sulfonamides and their use as parasiticides | PFIZER INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-7687533-B2 | N-(1-arylpyrazol-4l) sulfonamides and their use as parasiticides | PFIZER INC. (US) | 2010-03-30 | — | — | US | disclosed |
| US-20100075956-A1 | N-(1-ARYLPYRAZOL-4L)SULFONAMIDES AND THEIR USE AS PARASITICIDES | PFIZER INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-20080261940-A1 | N-(1-Arylpyrazol-4L) Sulfonamides and their Use as Parasiticides | ZOETIS LLC | 2008-10-23 | — | — | US | disclosed |
| EP-1735284-A1 | N-(1-ARYLPYRAZOL-4L)SULFONAMIDES AND THEIR USE AS PARASITICIDES | Pfizer Limited (GB) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005090313-A1 | N-(1-ARYLPYRAZOL-4L)SULFONAMIDES AND THEIR USE AS PARASITICIDES | PFIZER LIMITED (GB) | 2005-09-29 | — | — | WO | disclosed |