SCHEMBL4835244

SCHEMBL4835244

C=CC(Cl)S(=O)(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3739659 0.78
SCHEMBL944358 0.73
SCHEMBL3238308 0.71
SCHEMBL6434990 0.71
Hydrochloric Acid SCHEMBL11820007 0.71
SCHEMBL6434988 0.71
SCHEMBL2868733 0.68
SCHEMBL253091 0.67
SCHEMBL1652638 0.67
SCHEMBL5409448 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7285926-A None JP disclosed
CN-111018891-B Substituted amino six-membered saturated heteroalicyclic as long acting DPP-IV inhibitors 正大天晴药业集团股份有限公司 2021-12-03 CN disclosed
US-20210015933-A1 BIOACTIVE CARBOXYLIC ACID TYPE COMPOUND-POLYMER CONJUGATE, AND METHOD FOR MANUFACTURING THE SAME SEIKAGAKU CORPORATION (JP) 2021-01-21 US disclosed
US-20200138964-A1 TERTIARY AMINE COMPOUND OR IMINE COMPOUND-POLYMER CONJUGATE AND PRODUCTION METHOD THEREFOR SEIKAGAKU CORPORATION (JP) 2020-05-07 US disclosed
CN-111018891-A Substituted amino six-membered saturated heteroalicyclic as long acting DPP-IV inhibitors 正大天晴药业集团股份有限公司 2020-04-17 CN disclosed
WO-2019189876-A1 (CARBOXYLIC ACID-TYPE COMPOUND)-POLYMER CONJUGATE HAVING BIOLOGICAL ACTIVITY, AND METHOD FOR PRODUCING SAME 生化学工業株式会社 2019-10-03 WO disclosed
US-10155775-B2 Substituted amino six-membered saturated heteroalicycles as long-acting DPP-IV inhibitors CENTAURUS BIOPHARMA CO., LTD. (CN) 2018-12-18 US disclosed
US-20180111950-A1 SUBSTITUTED AMINO SIX-MEMBERED SATURATED HETEROALICYCLES AS LONG-ACTING DPP-IV INHIBITORS CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2018-04-26 US disclosed
EP-3257857-A1 SUBSTITUTED AMINO SIX-MEMBERED SATURATED HETEROCYCLIC FAT USED AS LONG-ACTING DPP-IV INHIBITOR Centaurus BioPharma Co., Ltd. (CN) 2017-12-20 EP disclosed
CN-103992251-A Preparation method of chloroalkyl sulfonyl chloride JING LIQIU 2014-08-20 CN disclosed
EP-1020443-B1 PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF AZWELL INC (JP) 2003-09-10 EP disclosed
WO-2003067332-A2 SULFONATE DERIVATIVES AND THE USE THEROF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-08-14 WO disclosed
US-6172228-B1 Process for producing piperazinesulfonamide derivatives and salts thereof AZWELL INC. (JP) 2001-01-09 US disclosed
EP-1020443-A1 PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF Azwell Inc. (JP) 2000-07-19 EP disclosed
EP-1020437-A1 PROCESS FOR PRODUCING HALOGENOALKYLSULFONAMIDE DERIVATIVES Azwell Inc. (JP) 2000-07-19 EP disclosed
JP-H07285926-A METHOD FOR PRODUCING CHLOROALKYLSULFONYL CHLORIDE SHIONOGI & CO LTD 1995-10-31 JP disclosed
US-4228233-A CYAN DYE FORMING, COLORLESS COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-10-14 US disclosed
US-4095983-A Photographic material comprising cyclic sulfonamide substituted yellow color couplers AGFA-GEVAERT AG (DT) 1978-06-20 US disclosed
US-4041051-A 1-AMINO-4-HYDROXY-2-(P-METHOXY OR ETHOXY-BENZENESULFONYLOXY)-ANTHRAQUINONE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-09 US disclosed
US-3979454-A Process for the production of alkyl sulphonic acid hydroxy alkyl amides BAYER AKTIENGESELLSCHAFT (DT) 1976-09-07 US disclosed