Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365427 | 0.84 | ROCK2 (0.39) | — | |
| SCHEMBL4379357 | 0.81 | GPR142 (0.32) | GPR142MEN1KMT2AMAPT | |
| SCHEMBL4367880 | 0.81 | ROCK2 (0.39) | — | |
| SCHEMBL4367897 | 0.81 | ROCK2 (0.39) | — | |
| SCHEMBL4375050 | 0.80 | EGLN1 (0.41) | MEN1KMT2AMAPT | |
| SCHEMBL4371828 | 0.80 | NPY5R (0.32) | GPR142 | |
| SCHEMBL4376105 | 0.79 | MAPK1 (0.40) | — | |
| SCHEMBL4368955 | 0.79 | METAP1 (0.32) | — | |
| SCHEMBL4365489 | 0.78 | ROCK2 (0.40) | — | |
| SCHEMBL4372975 | 0.78 | MTOR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581217-A4 | CARBONYLAMINO-BENZIMIDAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1581217-A1 | CARBONYLAMINO-BENZIMIDAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004041277-A1 | CARBONYLAMINO-BENZIMIDAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2004-05-21 | — | — | WO | disclosed |