Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023150 | 0.83 | SMN1; SMN2 (0.47) | MAPTMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL4023565 | 0.81 | GAA (0.49) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL4846761 | 0.78 | RAB9A (0.46) | MAPTKMT2AL3MBTL1GAANPC1 | |
| SCHEMBL4029331 | 0.78 | GAA (0.46) | MAPTMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4024084 | 0.74 | GAA (0.49) | MAPTMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4020612 | 0.74 | EPHB3 (0.43) | MAPTMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4026774 | 0.73 | TACR1 (0.46) | MAPTFFAR1LMNATACR1 | |
| SCHEMBL4027203 | 0.71 | DHFR (0.40) | MAPTMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4030229 | 0.70 | HTT (0.47) | MAPTMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL3363237 | 0.69 | MGAM (0.45) | MEN1KMT2AATMGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014054-A2 | BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR | GLAXO GROUP LIMTED (GB) | 2007-02-01 | — | — | WO | disclosed |