Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | POLA1 | P09884 | 2/20 | 0.51 |
| ▸ | POLD1 | P28340 | 1/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011098 | 0.84 | P2RY2 (0.62) | POLA1P2RY2P2RY4P2RY6 | |
| SCHEMBL7240891 | 0.83 | POLB (0.52) | POLBPOLA1POLD1P2RY2P2RY4 | |
| SCHEMBL9392106 | 0.83 | POLA1 (0.51) | POLBPOLA1POLD1P2RY2P2RY4 | |
| SCHEMBL18486642 | 0.82 | P2RY6 (0.59) | POLA1P2RY2P2RY4P2RY6 | |
| SCHEMBL29862897 | 0.81 | P2RY2 (0.45) | P2RY2P2RY4P2RY6 | |
| SCHEMBL29723202 | 0.80 | POLB (0.51) | POLBPOLA1POLD1P2RY2P2RY4 | |
| SCHEMBL29538414 | 0.80 | POLB (0.51) | POLBPOLA1POLD1P2RY2P2RY4 | |
| SCHEMBL3715513 | 0.80 | POLB (0.51) | POLBPOLA1POLD1P2RY2P2RY4 | |
| SCHEMBL31742537 | 0.80 | POLB (0.51) | POLBPOLA1POLD1P2RY2P2RY4 | |
| SCHEMBL30874770 | 0.80 | P2RY6 (0.53) | P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007530049-A | — | — | 2007-11-01 | — | — | JP | claimed |
| EP-1735470-A1 | QUANTITATIVE ASSAY FOR DETECTION OF NEWLY SYNTHESIZED RNA IN A CELL-FREE SYSTEM AND IDENTIFICATION OF RNA SYNTHESIS INHIBITORS | Achillion Pharmaceuticals, Inc. (US) | 2006-12-27 | — | — | EP | claimed |
| WO-2005095655-A1 | QUANTITATIVE ASSAY FOR DETECTION OF NEWLY SYNTHESIZED RNA IN A CELL-FREE SYSTEM AND IDENTIFICATION OF RNA SYNTHESIS INHIBITORS | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |
| EP-1735470-A1 | QUANTITATIVE ASSAY FOR DETECTION OF NEWLY SYNTHESIZED RNA IN A CELL-FREE SYSTEM AND IDENTIFICATION OF RNA SYNTHESIS INHIBITORS | Achillion Pharmaceuticals, Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005095655-A1 | QUANTITATIVE ASSAY FOR DETECTION OF NEWLY SYNTHESIZED RNA IN A CELL-FREE SYSTEM AND IDENTIFICATION OF RNA SYNTHESIS INHIBITORS | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | disclosed |