SCHEMBL541141

SCHEMBL541141

C=C(C)C(=O)OCCCCCCOP(=O)([O-])OCCCC[N+](C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
AKT1 P31749 2/20 0.52
ESR1 P03372 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
CDC25A P30304 1/20 0.52
AGTR1 P30556 1/20 0.52
ADRA1A P35348 1/20 0.52
KCNH2 Q12809 1/20 0.52
TSHR P16473 2/20 0.50
ADRA1D P25100 1/20 0.44
PTAFR P25105 1/20 0.44
HTR1D P28221 1/20 0.44
HTR2C P28335 1/20 0.44
ADRA1B P35368 1/20 0.44
DRD3 P35462 1/20 0.44
TMEM97 Q5BJF2 1/20 0.44
MAPT P10636 1/20 0.41
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15393208 1.00 LMNA (0.52) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1260913 1.00 LMNA (0.52) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL15393394 1.00 LMNA (0.52) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1260055 0.99 AKT1 (0.50) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1260696 0.97 AKT1 (0.49) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1260678 0.97 LMNA (0.52) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL15393527 0.97 LMNA (0.52) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL15393520 0.97 LMNA (0.52) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1260704 0.97 LMNA (0.52) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1261300 0.96 AKT1 (0.50) LMNAAKT1ESR1ADORA3CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240189121-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2024-06-13 US claimed
EP-3666299-B1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP (US) 2024-05-15 EP claimed
US-11903850-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2024-02-20 US claimed
US-20230036800-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2023-02-02 US claimed
US-11406514-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2022-08-09 US claimed
US-11369497-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2022-06-28 US claimed
US-20210068991-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2021-03-11 US claimed
US-10835393-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2020-11-17 US claimed
EP-3666299-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS Covidien LP (US) 2020-06-17 EP claimed
EP-3400973-B1 METHOD OF MANUFACTURING ANTI-THROMBOGENIC MEDICAL DEVICES COVIDIEN LP (US) 2020-02-12 EP claimed
WO-2015077081-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP (US) 2015-05-28 WO claimed
US-20150148882-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2015-05-28 US claimed
EP-2875833-A1 Anti-thrombogenic medical devices and methods Covidien LP (US) 2015-05-27 EP claimed
US-20150140344-A1 COATED MEDICAL DEVICES COVIDIEN LP 2015-05-21 US claimed
EP-2801401-A1 OUTSTANDINGLY CONTAMINATION RESISTANT REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR LG Chem, Ltd. (KR) 2014-11-12 EP claimed
US-8646617-B2 Reverse osmosis membrane having good antifouling properties and method of manufacturing the same LG CHEM, LTD. (KR) 2014-02-11 US claimed
US-20130306550-A1 REVERSE OSMOSIS MEMBRANE HAVING GOOD ANTIFOULING PROPERTIES AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2013-11-21 US claimed
US-20100094339-A1 COATING COMPOSITIONS COVIDIEN LP 2010-04-15 US claimed
EP-2120824-A1 COATING COMPOSITIONS Tyco Healthcare Group LP (US) 2009-11-25 EP claimed
WO-2008143654-A1 COATING COMPOSITIONS TYCO HEALTHCARE GROUP LP (US) 2008-11-27 WO claimed