SCHEMBL1260055

SCHEMBL1260055

C=C(C)C(=O)OCCCCOP(=O)([O-])OCCCC[N+](C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 2/20 0.50
LMNA P02545 1/20 0.50
ESR1 P03372 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
CDC25A P30304 1/20 0.50
AGTR1 P30556 1/20 0.50
ADRA1A P35348 1/20 0.50
KCNH2 Q12809 1/20 0.50
TSHR P16473 2/20 0.47
ADRA1D P25100 1/20 0.42
PTAFR P25105 1/20 0.42
HTR1D P28221 1/20 0.42
HTR2C P28335 1/20 0.42
ADRA1B P35368 1/20 0.42
DRD3 P35462 1/20 0.42
TMEM97 Q5BJF2 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15393208 0.99 LMNA (0.52) AKT1LMNAESR1ADORA3CDC25A
SCHEMBL15393394 0.99 LMNA (0.52) AKT1LMNAESR1ADORA3CDC25A
SCHEMBL541141 0.99 LMNA (0.52) AKT1LMNAESR1ADORA3CDC25A
SCHEMBL1260913 0.99 LMNA (0.52) AKT1LMNAESR1ADORA3CDC25A
SCHEMBL1260696 0.99 AKT1 (0.49) AKT1LMNAESR1ADORA3CDC25A
SCHEMBL1261300 0.97 AKT1 (0.50) AKT1LMNAESR1ADORA3CDC25A
Phosphoric Acid SCHEMBL2034350 0.96 AKT1 (0.47) AKT1LMNAESR1ADORA3CDC25A
SCHEMBL1260809 0.96 AKT1 (0.49) AKT1LMNAESR1ADORA3CDC25A
SCHEMBL1260704 0.96 LMNA (0.52) AKT1LMNAESR1ADORA3CDC25A
SCHEMBL15393520 0.96 LMNA (0.52) AKT1LMNAESR1ADORA3CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2801401-B1 OUTSTANDINGLY CONTAMINATION RESISTANT REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR LG CHEMICAL LTD (KR) 2018-12-12 EP claimed
EP-2801401-A1 OUTSTANDINGLY CONTAMINATION RESISTANT REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR LG Chem, Ltd. (KR) 2014-11-12 EP claimed
US-8646617-B2 Reverse osmosis membrane having good antifouling properties and method of manufacturing the same LG CHEM, LTD. (KR) 2014-02-11 US claimed
US-20130306550-A1 REVERSE OSMOSIS MEMBRANE HAVING GOOD ANTIFOULING PROPERTIES AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2013-11-21 US claimed
EP-2801401-B1 OUTSTANDINGLY CONTAMINATION RESISTANT REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR LG CHEMICAL LTD (KR) 2018-12-12 EP disclosed
US-9216241-B2 Medical device and method for producing the same KYOCERA MEDICAL CORPORATION (JP) 2015-12-22 US disclosed
EP-2801401-A1 OUTSTANDINGLY CONTAMINATION RESISTANT REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR LG Chem, Ltd. (KR) 2014-11-12 EP disclosed
EP-2233159-B1 MEDICAL DEVICE AND METHOD FOR MANUFACTURE THEREOF KYOCERA MEDICAL CORP (JP) 2014-05-14 EP disclosed
US-8646617-B2 Reverse osmosis membrane having good antifouling properties and method of manufacturing the same LG CHEM, LTD. (KR) 2014-02-11 US disclosed
US-20130306550-A1 REVERSE OSMOSIS MEMBRANE HAVING GOOD ANTIFOULING PROPERTIES AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2013-11-21 US disclosed
US-20110027757-A1 MEDICAL DEVICE AND METHOD FOR PRODUCING THE SAME Japan Medical Materials Corporation and The University of Tokyo 2011-02-03 US disclosed
EP-2233159-A1 MEDICAL DEVICE AND METHOD FOR MANUFACTURE THEREOF Japan Medical Materials Corporation (JP) 2010-09-29 EP disclosed
US-20070287094-A1 Planographic Printing Plate, Planographic Printing Plate Material, Support for Planographic Printing Plate Material, and Planographic Printing Method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-12-13 US disclosed
US-20070065379-A1 Microcapsules having an aqueous core and their use in cosmetics L'OREAL (FR) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070065379-A1 Microcapsules having an aqueous core and their use in cosmetics PHOSPHO1, SGMS1, CUTA AKT1 668/4885LMNA 737/4885ESR1 3995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.