Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.60 |
| ▸ | MET | P08581 | 10/20 | 0.52 |
| ▸ | FLT3 | P36888 | 3/20 | 0.52 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371859 | 0.90 | AXL (0.65) | AXLMETFLT3FGFR2KDR | |
| SCHEMBL29693573 | 0.90 | AXL (0.65) | AXLMETFLT3FGFR2KDR | |
| SCHEMBL3544369 | 0.86 | MET (0.58) | AXLMETFLT3KDR | |
| SCHEMBL168001 | 0.86 | AXL (0.54) | AXLMETFLT3KDR | |
| SCHEMBL2744533 | 0.86 | MET (0.60) | AXLMETFLT3FGFR2KDR | |
| SCHEMBL5571100 | 0.83 | MET (0.57) | AXLMETFLT3KDREGFR | |
| SCHEMBL371845 | 0.82 | AXL (0.61) | AXLMETFLT3KDREGFR | |
| SCHEMBL166914 | 0.81 | AXL (0.67) | AXLMETFGFR2KDRSRC | |
| SCHEMBL15338423 | 0.80 | EGFR (0.63) | AXLMETFLT3FGFR2KDR | |
| Hydrochloric Acid SCHEMBL30388215 | 0.80 | AXL (0.66) | AXLMETFGFR2KDRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007033196-A1 | MET KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-22 | — | — | WO | disclosed |