SCHEMBL54121

SCHEMBL54121

Nc1ccc(CO)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL864912 0.97 ALDH1A1 (0.55)
SCHEMBL1309905 0.92 CYP3A4 (0.58)
Bicarbonate SCHEMBL932925 0.89 TSHR (0.48)
SCHEMBL12973296 0.85 APP (0.58)
SCHEMBL12653890 0.85 MAPT (0.64)
SCHEMBL23748641 0.85 LTA4H (0.65)
SCHEMBL18364910 0.85 ALDH1A1 (0.44)
SCHEMBL15836247 0.85 MAPT (0.54)
SCHEMBL41775 0.83 TSHR (0.67)
Aminobenzoic Acid SCHEMBL2107999 0.82 ALDH1A1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9143 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070936-A Nanometer material based on supermolecule polypeptide-drug coupling prodrug, and preparation method and application thereof 中国医学科学院生物医学工程研究所 2026-05-22 CN claimed
CN-122059976-A Double-lock cascade activated fluorescent probe and preparation method and application thereof 福州大学 2026-05-19 CN claimed
CN-121136277-B Modified polypropylene composite material for sealing head and preparation method thereof 滁州熙诚环保科技股份有限公司 2026-05-19 CN claimed
CN-122036842-A Cathepsin B-sensitive fatty acid-irinotecan prodrug and albumin nanoparticle thereof, and preparation method and application thereof 沈阳药科大学 2026-05-15 CN claimed
CN-122036845-A Cathepsin B-sensitive fatty acid-doxorubicin prodrug, albumin nanoparticle thereof, and preparation method and application thereof 沈阳药科大学 2026-05-15 CN claimed
US-20260124311-A1 POLYMER-DRUG CONJUGATES FOR STING PATHWAY ACTIVATION UNIV VANDERBILT (US) 2026-05-07 US claimed
EP-4036149-B1 HETEROBIFUNCTIONAL MONODISPERSED POLYETHYLENE GLYCOL HAVING PEPTIDE LINKER NOF CORP (JP) 2026-04-29 EP claimed
US-12605458-B2 Antibody-drug conjugate having acidic self-stabilization junction SYSTIMMUNE, INC. (US) 2026-04-21 US claimed
EP-3494996-B1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 158P1D7 PROTEINS AGENSYS INC (US) 2026-04-15 EP claimed
US-20260083866-A1 COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-03-26 US claimed
CN-1203615-A Laccases with improved dyeing properties NOVO NORDISK AS (DK) 1998-12-30 CN claimed
US-5795869-A IMMUNOLOGY AND PROTECTION AGAINST NEUROTOXICITY FOR NERVOUS SYSTEM DISORDERS FIDIA S.P.A. (IT) 1998-08-18 US claimed
JP-H08507308-A 1996-08-06 JP claimed
EP-0688331-A1 NEW SULFATED LYSO-GANGLIOSIDE DERIVATIVES FIDIA S.p.A. (IT) 1995-12-27 EP claimed
EP-0624377-A2 Lysosomal enzyme-cleavable antitumor drug conjugates Bristol-Myers Squibb Company (US) 1994-11-17 EP claimed
WO-1994020516-A1 NEW SULFATED LYSO-GANGLIOSIDE DERIVATIVES FIDIA S.P.A. (IT) 1994-09-15 WO claimed
EP-0038357-A4 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS. UNIV ILLINOIS (US) 1982-03-22 EP claimed
EP-0038357-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS University of Illinois Foundation (US) 1981-10-28 EP claimed
WO-1981001145-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS UNIV ILLINOIS (US) 1981-04-30 WO claimed
US-3931418-A Process for the production of insulating coatings on electrical conductors DR. KURT HERBERTS & CO. GESELLSCHAFT MIT BESCHRANKTER HAFTUNG VORM. OTTO LOUIS HERBERTS (DT) 1976-01-06 US claimed