Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 11/20 | 0.79 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 2/20 | 0.59 |
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | CPA1 | P15085 | 2/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411759 | 1.00 | FPR2 (0.79) | FPR2FOLH1MMEACECPA1 | |
| SCHEMBL6375756 | 0.92 | FPR2 (0.81) | FPR2FOLH1MMEMEN1KMT2A | |
| SCHEMBL6375751 | 0.92 | FPR2 (0.81) | FPR2FOLH1MMEMEN1KMT2A | |
| SCHEMBL6381444 | 0.92 | FPR2 (0.81) | FPR2FOLH1MMEMEN1KMT2A | |
| SCHEMBL3450270 | 0.88 | FPR2 (0.76) | FPR2FOLH1MEN1KMT2A | |
| SCHEMBL6376189 | 0.88 | FPR2 (0.75) | FPR2FOLH1MEN1KMT2A | |
| SCHEMBL6376031 | 0.88 | FPR2 (1.00) | FPR2 | |
| SCHEMBL6375538 | 0.88 | FPR2 (0.75) | FPR2FOLH1MEN1KMT2A | |
| SCHEMBL6376315 | 0.88 | FPR2 (0.75) | FPR2FOLH1MEN1KMT2A | |
| SCHEMBL6379132 | 0.88 | FPR2 (0.76) | FPR2FOLH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202269-B2 | GlyT2 modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-04-10 | — | — | US | disclosed |
| US-20050119245-A1 | GlyT2 modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-06-02 | — | — | US | disclosed |
| WO-2005044810-A1 | GLYT2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119245-A1 | GlyT2 modulators | GLRB, GLRA1, GLRA2 | FPR2 3048/4885FOLH1 289/4885MME 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.