SCHEMBL6375756

SCHEMBL6375756

O=C(Nc1ccccc1)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 11/20 0.81
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
NAALAD2 Q9Y3Q0 2/20 0.63
FOLH1 Q04609 2/20 0.61
MME P08473 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6375751 1.00 FPR2 (0.81) FPR2MEN1KMT2ANAALAD2FOLH1
SCHEMBL6381444 1.00 FPR2 (0.81) FPR2MEN1KMT2ANAALAD2FOLH1
SCHEMBL5412166 0.92 FPR2 (0.79) FPR2MEN1KMT2AFOLH1MME
SCHEMBL5411759 0.92 FPR2 (0.79) FPR2MEN1KMT2AFOLH1MME
SCHEMBL6375538 0.90 FPR2 (0.75) FPR2MEN1KMT2ANAALAD2FOLH1
SCHEMBL3450270 0.90 FPR2 (0.76) FPR2MEN1KMT2ANAALAD2FOLH1
SCHEMBL6372964 0.90 FPR2 (1.00) FPR2MEN1KMT2ANAALAD2FOLH1
SCHEMBL6376189 0.90 FPR2 (0.75) FPR2MEN1KMT2ANAALAD2FOLH1
SCHEMBL6376031 0.90 FPR2 (1.00) FPR2
SCHEMBL6379132 0.90 FPR2 (0.76) FPR2MEN1KMT2ANAALAD2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4269119-B1 COLOUR DEVELOPER, THERMAL RECORDING MATERIAL, AND COATING MATERIAL FOR THERMAL RECORDING LAYERS SANKO CO LTD (JP) 2025-05-07 EP claimed
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US claimed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP claimed
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
EP-4269119-B1 COLOUR DEVELOPER, THERMAL RECORDING MATERIAL, AND COATING MATERIAL FOR THERMAL RECORDING LAYERS SANKO CO LTD (JP) 2025-05-07 EP disclosed
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
US-20240190816-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO., LTD. (JP) 2024-06-13 US disclosed
US-20240181797-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2024-06-06 US disclosed
US-11945769-B2 N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same SANKO CO., LTD. (JP) 2024-04-02 US disclosed
WO-2024043313-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, MICROENCAPSULATED PIGMENT USING SAID REVERSIBLE THERMOCHROMIC COMPOSITION, WRITING TOOL, AND TOY 三菱ケミカル株式会社 2024-02-29 WO disclosed
EP-4313612-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD Ricoh Company, Ltd. (JP) 2024-02-07 EP disclosed
EP-3677569-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2020-07-08 EP disclosed
CN-111032626-A N, N' -diaryl urea derivative, process for producing the same, and thermosensitive recording material using the same 三光株式会社 2020-04-17 CN disclosed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 US disclosed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 US disclosed
EP-3342599-A1 HEAT-SENSITIVE RECORDING MATERIAL Sanko Co., Ltd. (JP) 2018-07-04 EP disclosed
WO-2014138046-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN, INC. (US) 2014-09-12 WO disclosed
WO-2014138037-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2014-09-12 WO disclosed
US-20050137230-A1 Carboxamide derivatives DORSCH DIETER (DE) 2005-06-23 US disclosed
US-20040038858-A1 Carboxamide derivatives and their use in the treatment of thromboembolic diseases and tumours MERCK PATENT GMBH (DE) 2004-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 FPR2 622/4885MEN1 830/4885KMT2A 2251/4885
US-20050137230-A1 Carboxamide derivatives F11, F12, F2 FPR2 766/4885MEN1 218/4885KMT2A 1277/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 FPR2 565/4885MEN1 812/4885KMT2A 1982/4885
US-11945769-B2 N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same SCN1A, SCN1B, NAAA FPR2 3200/4885MEN1 1054/4885KMT2A 540/4885
US-20240190816-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SCN1A, SCN1B, SCN2A FPR2 1776/4885MEN1 1816/4885KMT2A 335/4885
US-20040038858-A1 Carboxamide derivatives and their use in the treatment of thromboembolic diseases and tumours CNR2, CNR1, HCAR2 FPR2 176/4885MEN1 3354/4885KMT2A 697/4885
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA FPR2 167/4885MEN1 2981/4885KMT2A 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.