Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859323 | 0.97 | XDH (0.73) | XDHALDH1A1HPGD | |
| SCHEMBL7861730 | 0.96 | XDH (0.71) | XDHALDH1A1HPGD | |
| SCHEMBL7865106 | 0.89 | XDH (0.59) | XDHALDH1A1HPGD | |
| SCHEMBL5412822 | 0.88 | XDH (0.71) | XDH | |
| SCHEMBL7860397 | 0.86 | XDH (0.58) | XDHALDH1A1HPGD | |
| SCHEMBL5414808 | 0.85 | XDH (0.71) | XDH | |
| SCHEMBL5419378 | 0.85 | XDH (0.74) | XDH | |
| SCHEMBL29693309 | 0.85 | XDH (1.00) | XDH | |
| SCHEMBL440021 | 0.85 | XDH (1.00) | XDH | |
| SCHEMBL7860437 | 0.85 | XDH (0.57) | XDHALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105708-C | 1-phenylpyrazole compounds and pharmaceutical use thereof | EFUKU CO LTD (JP) | 2003-04-16 | — | — | CN | claimed |
| EP-0936217-B1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | WELFIDE CORP (JP) | 2001-11-07 | — | — | EP | claimed |
| US-6015829-A | 1-phenylpyrazole compounds and medicinal application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-01-18 | — | — | US | claimed |
| CN-1240432-A | 1-phenylpyrazole compounds and medicinal application thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2000-01-05 | — | — | CN | claimed |
| EP-0936217-A1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-08-18 | — | — | EP | claimed |
| US-7208514-B2 | Tumorigenesis inhibitor | MITSUBISHI PHARMA CORPORATION (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060106036-A1 | Tumorigenesis inhibitor | MITSUBISHI PHARMA CORPORATION (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1609479-A1 | TUMORIGENESIS INHIBITOR | Mitsubishi Pharma Corporation (JP) | 2005-12-28 | — | — | EP | disclosed |
| CN-1105708-C | 1-phenylpyrazole compounds and pharmaceutical use thereof | EFUKU CO LTD (JP) | 2003-04-16 | — | — | CN | disclosed |
| EP-0936217-B1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | WELFIDE CORP (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6015829-A | 1-phenylpyrazole compounds and medicinal application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| CN-1240432-A | 1-phenylpyrazole compounds and medicinal application thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2000-01-05 | — | — | CN | disclosed |
| EP-0936217-A1 | 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106036-A1 | Tumorigenesis inhibitor | XDH, LOXL1, LOX | XDH 1/4885ALDH1A1 78/4885HPGD 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.