Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 1.00 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730825 | 0.88 | PTPN1 (0.93) | PTPN1EYA3TTRNR1H4 | |
| SCHEMBL5411571 | 0.84 | PTPN1 (1.00) | PTPN1EYA3NQO1TTR | |
| SCHEMBL5416428 | 0.84 | PTPN1 (1.00) | PTPN1EYA3NQO1TTR | |
| SCHEMBL6735103 | 0.80 | PTPN1 (0.75) | PTPN1EYA3TTRNR1H4 | |
| SCHEMBL3864688 | 0.78 | PTPN1 (0.71) | PTPN1EYA3TTRNR1H4 | |
| SCHEMBL5764063 | 0.78 | PTPN1 (0.83) | PTPN1EYA3 | |
| SCHEMBL10449009 | 0.76 | PTPN1 (0.62) | PTPN1EYA3TTR | |
| SCHEMBL4670176 | 0.76 | PTPN1 (0.61) | PTPN1EYA3TTRNR1H4 | |
| SCHEMBL4673730 | 0.76 | PTPN1 (0.61) | PTPN1EYA3TTRNR1H4 | |
| SCHEMBL5413746 | 0.75 | PTPN1 (1.00) | PTPN1EYA3NQO1TTRNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291639-B2 | Aryloxy-acetic acid compounds useful as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | WYETH (US) | 2007-11-06 | — | — | US | claimed |