Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839249 | 0.81 | MAPT (0.59) | MAPTCYP1A2NPC1MEN1ALDH1A1 | |
| SCHEMBL28164633 | 0.78 | MAPT (0.47) | MAPTCYP1A2NPC1MEN1ALDH1A1 | |
| SCHEMBL26654861 | 0.78 | NPC1 (0.47) | MAPTCYP1A2NPC1MEN1ALDH1A1 | |
| SCHEMBL26655206 | 0.76 | MAPT (0.46) | MAPTCYP1A2NPC1MEN1ALDH1A1 | |
| SCHEMBL5414561 | 0.74 | MAPT (0.47) | MAPTCYP1A2NPC1MEN1ALDH1A1 | |
| SCHEMBL7071245 | 0.74 | MAPT (0.47) | MAPTCYP1A2NPC1MEN1ALDH1A1 | |
| SCHEMBL7061161 | 0.73 | ALDH1A1 (0.66) | MAPTCYP1A2NPC1MEN1ALDH1A1 | |
| SCHEMBL21655105 | 0.73 | ALDH1A1 (0.45) | MAPTCYP1A2NPC1MEN1ALDH1A1 | |
| SCHEMBL21655108 | 0.72 | KCNH2 (0.50) | NPC1MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL16719414 | 0.72 | NPC1 (0.56) | MAPTCYP1A2NPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307137-B2 | CROSSLINKING SHELL-CORE POLYMER | HONEYWELL INTERNATIONAL INC. (US) | 2007-12-11 | — | — | US | claimed |
| EP-1373358-A4 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | HONEYWELL INT INC (US) | 2005-03-16 | — | — | EP | claimed |
| US-20040158024-A1 | CROSSLINKING SHELL-CORE POLYMER | HONEYWELL INTERNATIONAL INC. | 2004-08-12 | — | — | US | claimed |
| EP-1373358-A1 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | Honeywell International, Inc. (US) | 2004-01-02 | — | — | EP | claimed |
| WO-2002081546-A1 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | HONEYWELL INTERNATIONAL INC. (US) | 2002-10-17 | — | — | WO | claimed |
| US-7307137-B2 | CROSSLINKING SHELL-CORE POLYMER | HONEYWELL INTERNATIONAL INC. (US) | 2007-12-11 | — | — | US | disclosed |
| US-20050182151-A1 | Low dielectric constant polyorganosilicon materials generated from polycarbosilanes | APEN PAUL (US) | 2005-08-18 | — | — | US | disclosed |
| EP-1373358-A4 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | HONEYWELL INT INC (US) | 2005-03-16 | — | — | EP | disclosed |
| US-6841256-B2 | Low dielectric constant polyorganosilicon materials generated from polycarbosilanes | HONEYWELL INTERNATIONAL INC. (US) | 2005-01-11 | — | — | US | disclosed |
| US-20040158024-A1 | CROSSLINKING SHELL-CORE POLYMER | HONEYWELL INTERNATIONAL INC. | 2004-08-12 | — | — | US | disclosed |
| EP-1373358-A1 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | Honeywell International, Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081546-A1 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | HONEYWELL INTERNATIONAL INC. (US) | 2002-10-17 | — | — | WO | disclosed |