SCHEMBL541534

SCHEMBL541534

C=C(C)C(=O)OCCC(C[N+](CC)(CC)CC)OP(=O)(O)O

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.39
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2037753 0.92 TSHR (0.43) THRBTSHRALDH1A1
SCHEMBL2035969 0.91 TSHR (0.46) THRBTSHRALDH1A1
SCHEMBL2036004 0.90 TSHR (0.48) THRBTSHR
SCHEMBL541549 0.90 TSHR (0.40) THRBTSHRALDH1A1
SCHEMBL2324344 0.89 THRB (0.36) THRBTSHRALDH1A1
SCHEMBL3652753 0.88 THRB (0.39) THRBTSHRALDH1A1
SCHEMBL541927 0.87 TSHR (0.44) THRBTSHR
SCHEMBL176508 0.86 THRB (0.38) THRBTSHRALDH1A1
SCHEMBL2051067 0.86 TSHR (0.39) THRBTSHRALDH1A1
Methacrylic Acid SCHEMBL3884365 0.83 SMN1; SMN2 (0.36) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240189121-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2024-06-13 US claimed
EP-3666299-B1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP (US) 2024-05-15 EP claimed
US-11903850-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2024-02-20 US claimed
US-20230036800-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2023-02-02 US claimed
US-11406514-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2022-08-09 US claimed
US-11369497-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2022-06-28 US claimed
US-20210068991-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2021-03-11 US claimed
US-10835393-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2020-11-17 US claimed
EP-3666299-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS Covidien LP (US) 2020-06-17 EP claimed
EP-3400973-B1 METHOD OF MANUFACTURING ANTI-THROMBOGENIC MEDICAL DEVICES COVIDIEN LP (US) 2020-02-12 EP claimed
EP-2875833-B1 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2018-08-08 EP claimed
US-20170232156-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2017-08-17 US claimed
US-9668890-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2017-06-06 US claimed
US-20150148882-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2015-05-28 US claimed
WO-2015077081-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP (US) 2015-05-28 WO claimed
EP-2875833-A1 Anti-thrombogenic medical devices and methods Covidien LP (US) 2015-05-27 EP claimed
US-20150140344-A1 COATED MEDICAL DEVICES COVIDIEN LP 2015-05-21 US claimed
US-20100094339-A1 COATING COMPOSITIONS COVIDIEN LP 2010-04-15 US claimed
EP-2120824-A1 COATING COMPOSITIONS Tyco Healthcare Group LP (US) 2009-11-25 EP claimed
WO-2008143654-A1 COATING COMPOSITIONS TYCO HEALTHCARE GROUP LP (US) 2008-11-27 WO claimed