SCHEMBL2324344

SCHEMBL2324344

C=C(C)C(=O)OCCC(C[N+](CO)(CO)CO)OP(=O)(O)O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL541534 0.89 THRB (0.40) THRBTSHRALDH1A1
SCHEMBL541549 0.87 TSHR (0.40) THRBTSHRALDH1A1
SCHEMBL176508 0.86 THRB (0.38) THRBTSHRALDH1A1
SCHEMBL541927 0.85 TSHR (0.44) THRBTSHR
Methacrylic Acid SCHEMBL3884365 0.83 SMN1; SMN2 (0.36) THRBTSHRALDH1A1
SCHEMBL541607 0.82 THRB (0.37) THRBTSHRALDH1A1
SCHEMBL2037753 0.82 TSHR (0.43) THRBTSHRALDH1A1
SCHEMBL2035969 0.81 TSHR (0.46) THRBTSHRALDH1A1
SCHEMBL28127563 0.80 THRB (0.40) THRBTSHRALDH1A1
SCHEMBL692769 0.80 THRB (0.40) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252531-B2 Using biopolymer comprising phosphorylcholine-like groups to prevent non-specific hybridization of nucleotide sequence; drug screening NOF CORPORATION (JP) 2012-08-28 US disclosed
US-7993052-B2 Agitation mixer and feed pipe structure NOF CORPORATION (JP) 2011-08-09 US disclosed
EP-1428890-B1 METHOD OF JUDGING MISMATCH BETWEEN SINGLE-STRANDED NUCLEIC ACID MOLECULES NOF CORP (JP) 2008-08-06 EP disclosed
US-20080080304-A1 AGITATION METHOD, AGITATION MIXER, AND FEED PIPE STRUCTURE NOF CORPORATION (JP) 2008-04-03 US disclosed
US-20040265823-A1 Method of judging mismatch between single-stranded nucleic acid molecules NOF CORPORATION (JP) 2004-12-30 US disclosed
US-20040219546-A1 Nonspecific hydridization inhibitors, clinical examination reagents and clinical examination method NOF CORPORATION (JP) 2004-11-04 US disclosed
EP-1428890-A1 METHOD OF JUDGING MISMATCH BETWEEN SINGLE−STRANDED NUCLEIC ACID MOLECULES The Circle for the Promotion of Science and Engineering (JP) 2004-06-16 EP disclosed
EP-1391519-A1 NONSPECIFIC HYBRIDIZATION INHIBITORS, CLINICAL EXAMINATION REAGENTS AND CLINICAL EXAMINATION METHOD NOF CORPORATION (JP) 2004-02-25 EP disclosed
EP-0767212-B1 PROCESS FOR PRODUCING AN AQUEOUS SOLUTION OF PHOSPHORYLCHOLINE GROUP BEARING POLYMER AND AQUEOUS SOLUTION OF PHOSPHORYLCHOLINE GROUP BEARING POLYMER NOF CORP (JP) 2001-07-18 EP disclosed
US-6204324-B1 AN ETHYLENICALLY UNSATURATED POLYMERIZABLE MONOMER HAVING THE PHOSPHORYLCHOLINE GROUP IS POLYMERIZED IN THE PRESENCE OF A NON-METAL POLYMERIZATION INITIATOR SOLUTION CONTAINING PEROXY OR AZO COMPOUNDS NOF CORPORATION (JP) 2001-03-20 US disclosed
EP-0767212-A1 PROCESS FOR PRODUCING AN AQUEOUS SOLUTION OF PHOSPHORYLCHOLINE GROUP BEARING POLYMER AND AQUEOUS SOLUTION OF PHOSPHORYLCHOLINE GROUP BEARING POLYMER Japan Science and Technology Corporation (JP) 1997-04-09 EP disclosed