SCHEMBL541535

SCHEMBL541535

C=C(C)C(=O)OCCC(COP(=O)([O-])O)[N+](CC)(CC)CC

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
TSHR P16473 3/20 0.37
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2036641 0.91 THRB (0.39) THRBTSHRALDH1A1
SCHEMBL541550 0.90 TSHR (0.38) THRBTSHR
SCHEMBL20582579 0.90 THRB (0.40) THRBTSHRALDH1A1
SCHEMBL541928 0.88 TSHR (0.43) THRBTSHR
SCHEMBL6851650 0.87 TSHR (0.38) THRBTSHRALDH1A1
SCHEMBL2041337 0.81 TSHR (0.39) THRBTSHRALDH1A1
SCHEMBL28874073 0.80 TSHR (0.40) THRBTSHRALDH1A1
SCHEMBL28637235 0.80 TSHR (0.40) THRBTSHR
SCHEMBL2037326 0.79 TSHR (0.43) THRBTSHR
SCHEMBL2037549 0.78 TSHR (0.44) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240189121-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2024-06-13 US claimed
EP-3666299-B1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP (US) 2024-05-15 EP claimed
US-11903850-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2024-02-20 US claimed
US-20230036800-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2023-02-02 US claimed
US-11406514-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2022-08-09 US claimed
US-11369497-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2022-06-28 US claimed
US-20210068991-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2021-03-11 US claimed
US-10835393-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2020-11-17 US claimed
EP-3666299-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS Covidien LP (US) 2020-06-17 EP claimed
EP-3400973-B1 METHOD OF MANUFACTURING ANTI-THROMBOGENIC MEDICAL DEVICES COVIDIEN LP (US) 2020-02-12 EP claimed
US-10137012-B2 2018-11-27 US claimed
EP-3400973-A1 METHOD OF MANUFACTURING ANTI-THROMBOGENIC MEDICAL DEVICES Covidien LP (US) 2018-11-14 EP claimed
EP-2875833-B1 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2018-08-08 EP claimed
US-20170232156-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2017-08-17 US claimed
US-9668890-B2 Anti-thrombogenic medical devices and methods COVIDIEN LP (US) 2017-06-06 US claimed
US-20150148882-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP 2015-05-28 US claimed
WO-2015077081-A1 ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS COVIDIEN LP (US) 2015-05-28 WO claimed
EP-2875833-A1 Anti-thrombogenic medical devices and methods Covidien LP (US) 2015-05-27 EP claimed
US-20150140344-A1 COATED MEDICAL DEVICES COVIDIEN LP 2015-05-21 US claimed
US-20100094339-A1 COATING COMPOSITIONS COVIDIEN LP 2010-04-15 US claimed