Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.34 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541465 | 0.92 | TSHR (0.41) | THRBCHRM5CHRM1CHRM3TSHR | |
| SCHEMBL541116 | 0.92 | TSHR (0.38) | THRBCHRM5CHRM1CHRM3TSHR | |
| SCHEMBL541380 | 0.91 | TSHR (0.43) | THRBCHRM5CHRM1CHRM3TSHR | |
| SCHEMBL541209 | 0.90 | TSHR (0.46) | THRBCHRM5CHRM1CHRM3TSHR | |
| SCHEMBL541396 | 0.90 | TSHR (0.46) | THRBCHRM5CHRM1CHRM3TSHR | |
| SCHEMBL3652753 | 0.89 | THRB (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL3655604 | 0.88 | TSHR (0.43) | THRBTSHRALDH1A1 | |
| SCHEMBL176508 | 0.87 | THRB (0.38) | THRBCHRM5CHRM1CHRM3TSHR | |
| SCHEMBL541476 | 0.86 | TSHR (0.41) | THRBCHRM5CHRM1CHRM3TSHR | |
| SCHEMBL3649219 | 0.86 | TSHR (0.48) | THRBTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240189121-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2024-06-13 | — | — | US | claimed |
| EP-3666299-B1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP (US) | 2024-05-15 | — | — | EP | claimed |
| US-11903850-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2024-02-20 | — | — | US | claimed |
| US-20230036800-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2023-02-02 | — | — | US | claimed |
| US-11406514-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2022-08-09 | — | — | US | claimed |
| US-20220227954-A1 | POLYMERIC SURFACE HAVING REDUCED BIOMOLECULE ADHESION TO THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | OAKTREE FUND ADMINISTRATION, LLC | 2022-07-21 | — | — | US | claimed |
| US-11369497-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2022-06-28 | — | — | US | claimed |
| EP-3862384-A2 | POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | SiO2 Medical Products, Inc. (US) | 2021-08-11 | — | — | EP | claimed |
| US-20210068991-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2021-03-11 | — | — | US | claimed |
| US-10835393-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2020-11-17 | — | — | US | claimed |
| EP-3400973-A1 | METHOD OF MANUFACTURING ANTI-THROMBOGENIC MEDICAL DEVICES | Covidien LP (US) | 2018-11-14 | — | — | EP | claimed |
| EP-2875833-B1 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2018-08-08 | — | — | EP | claimed |
| US-20170232156-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2017-08-17 | — | — | US | claimed |
| US-9668890-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2017-06-06 | — | — | US | claimed |
| US-20150148882-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2015-05-28 | — | — | US | claimed |
| EP-2875833-A1 | Anti-thrombogenic medical devices and methods | Covidien LP (US) | 2015-05-27 | — | — | EP | claimed |
| US-20150140344-A1 | COATED MEDICAL DEVICES | COVIDIEN LP | 2015-05-21 | — | — | US | claimed |
| US-20100094339-A1 | COATING COMPOSITIONS | COVIDIEN LP | 2010-04-15 | — | — | US | claimed |
| EP-2120824-A1 | COATING COMPOSITIONS | Tyco Healthcare Group LP (US) | 2009-11-25 | — | — | EP | claimed |
| WO-2008143654-A1 | COATING COMPOSITIONS | TYCO HEALTHCARE GROUP LP (US) | 2008-11-27 | — | — | WO | claimed |