⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988849 | 0.69 | — | — | |
| SCHEMBL5416201 | 0.67 | — | — | |
| SCHEMBL10888909 | 0.67 | — | — | |
| SCHEMBL7465345 | 0.65 | — | — | |
| SCHEMBL2512586 | 0.63 | — | — | |
| SCHEMBL4038182 | 0.63 | — | — | |
| SCHEMBL2516922 | 0.60 | — | — | |
| SCHEMBL10981542 | 0.60 | ACHE (0.39) | — | |
| SCHEMBL1287796 | 0.60 | — | — | |
| SCHEMBL14967830 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2851367-B1 | PROCESS FOR THE PREPARATION OF A 2-AMINO-5,8-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE BY REACTION OF A 5-HALO-8-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-2-AMINE WITH AN ALKALI METAL ALKOXIDE IN AN ALCOHOLIC SOLVENT | DOW AGROSCIENCES LLC (US) | 2016-10-26 | — | — | EP | disclosed |
| EP-2576558-B9 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED-8-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-2-AMINES | DOW AGROSCIENCES LLC (US) | 2015-07-08 | — | — | EP | disclosed |
| EP-2851367-A1 | Process for the preparation of a 2-amino-5,8-alkoxy[1,2,4]triazolo[1,5-c]pyrimidine by reaction of a 5-halo-8-alkoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amine with an alkali metal alkoxide in an alcoholic solvent | Dow AgroSciences LLC (US) | 2015-03-25 | — | — | EP | disclosed |
| EP-2576558-B1 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED-8-ALKOXY[1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-2-AMINES | DOW AGROSCIENCES LLC (US) | 2014-12-24 | — | — | EP | disclosed |
| US-8143395-B2 | Process for the preparation of 5-substituted-8-alkoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amines | DOW AGROSCIENCES LLC (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110295003-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED-8-ALKOXY[1,2,4]TRIAZOLO[1,5-c]PYRIMIDIN-2-AMINES | DOW AGROSCIENCES LLC (US) | 2011-12-01 | — | — | US | disclosed |