SCHEMBL5416795

SCHEMBL5416795

C/C=C/C(=O)NC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
EPHX2 P34913 1/20 0.34
PTPRC P08575 1/20 0.34
PTPN2 P17706 1/20 0.34
PTPN1 P18031 1/20 0.34
PTPN7 P35236 1/20 0.34
DUSP3 P51452 1/20 0.34
GAA P10253 3/20 0.33
KDM4E B2RXH2 2/20 0.33
TGM2 P21980 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 1/20 0.31
FLT3 P36888 1/20 0.31
TYRO3 Q06418 1/20 0.31
MERTK Q12866 1/20 0.31
GAS6 Q14393 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5416803 1.00 POLB (0.35) POLBHDAC4HDAC6EPHX2PTPRC
SCHEMBL13297932 0.91 POLB (0.42) POLBHDAC4HDAC6EPHX2PTPRC
SCHEMBL6754431 0.86 PTPRC (0.43) POLBEPHX2PTPRCPTPN2PTPN1
SCHEMBL26680176 0.85 POLB (0.55) POLBHDAC4HDAC6EPHX2PTPRC
SCHEMBL5416747 0.83 POLB (0.33) POLBEPHX2PTPRCPTPN2PTPN1
SCHEMBL5416754 0.83 POLB (0.33) POLBEPHX2PTPRCPTPN2PTPN1
SCHEMBL68637 0.81 HDAC4 (0.36) HDAC4HDAC6GAAKDM4EKMT2A
SCHEMBL13290947 0.80 HDAC4 (0.32) POLBHDAC4HDAC6EPHX2
SCHEMBL9456416 0.77 EPHX2 (0.40) HDAC4HDAC6EPHX2GAAKDM4E
SCHEMBL108538 0.77 RECQL (0.47) POLBGAAKDM4EHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897312-B2 photoreceptors for electrophotography comprising undercoat layers, charge generation and charge transport layer on substrates; high resolution images KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-03-01 US disclosed
US-7229729-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MONOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-06-12 US disclosed
US-20060040193-A1 Organic photoreceptor, image forming apparatus, image forming method and image forming unit KONICA MINOLTA HOLDINGS, INC. (JP) 2006-02-23 US disclosed
US-20050064309-A1 photoreceptors for electrophotography comprising undercoat layers, charge generation and charge transport layer on substrates; high resolution images KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. 2005-03-24 US disclosed
US-20050037274-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2005-02-17 US disclosed
EP-0824127-B1 Water-type dispersion composition JSR CORP (JP) 2004-07-14 EP disclosed
US-6569586-B2 Comprises photosensitive layer and resin layer including organic polymer, siloxane component, and charge transfer component; durability KONICA CORPORATION (JP) 2003-05-27 US disclosed
US-20020076631-A1 Photoreceptor for forming electrostatic latent image KONICA CORPORATION (JP) 2002-06-20 US disclosed
US-20020051889-A1 Coating composition and cured product JSR CORPORATION (JP) 2002-05-02 US disclosed
US-5905109-A HYDROLYSIS AND CONDENSATION TO FORM POLYMERS WITH CATALYSTS JSR CORPORATION (JP) 1999-05-18 US disclosed
EP-0824127-A2 Water-type dispersion composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-02-18 EP disclosed