SCHEMBL68637

SCHEMBL68637

C=CC(=O)NC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
TEAD1 P28347 6/20 0.35
GAA P10253 3/20 0.34
KDM4E B2RXH2 2/20 0.34
FLT3 P36888 1/20 0.33
TYRO3 Q06418 1/20 0.33
MERTK Q12866 1/20 0.33
GAS6 Q14393 1/20 0.33
SMYD3 Q9H7B4 1/20 0.32
KMT2A Q03164 1/20 0.32
JAK3 P52333 1/20 0.32
TSHR P16473 1/20 0.31
BTK Q06187 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6754520 0.86 MAOB (0.39) TEAD1GAAKDM4ESMYD3KMT2A
SCHEMBL1050026 0.86 GAA (0.47) TEAD1GAAKDM4ESMYD3KMT2A
SCHEMBL13297932 0.85 POLB (0.42) HDAC4HDAC6GAAKDM4EFLT3
SCHEMBL110503 0.84 TEAD1 (0.35) TEAD1GAAKDM4ESMYD3KMT2A
SCHEMBL28804150 0.84 TEAD1 (0.38) TEAD1GAAKDM4ESMYD3KMT2A
SCHEMBL12863508 0.83 TEAD1 (0.34) TEAD1GAAKDM4ESMYD3KMT2A
SCHEMBL19424075 0.81 TEAD1 (0.33) TEAD1GAAKDM4ESMYD3KMT2A
SCHEMBL18073078 0.81 APLNR (0.37) TEAD1GAASMYD3TSHRBTK
SCHEMBL5416803 0.81 POLB (0.35) HDAC4HDAC6GAAKDM4EFLT3
SCHEMBL5416795 0.81 POLB (0.35) HDAC4HDAC6GAAKDM4EFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240059882-A1 PROPYLENE-BASED RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-02-22 US disclosed
EP-4279541-A1 PROPYLENE-BASED RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-22 EP disclosed
EP-3161078-B1 EXTRUDED FILM COMPRISING A FLUOROPOLYMER COMPOSITION INCLUDING AT LEAST ONE OLIGOMER 3M INNOVATIVE PROPERTIES CO (US) 2020-05-27 EP disclosed
US-10428220-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-01 US disclosed
EP-3234042-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 EP disclosed
US-10125251-B2 Fluoropolymer composition including at least one oligomer 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-11-13 US disclosed
US-20180037743-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2018-02-08 US disclosed
US-20180037743-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2018-02-08 US disclosed
US-20170198119-A1 COPOLYMERS INCLUDING A TRIAZINE GROUP AND COMPOSITIONS INCLUDING THEM 3M INNOVATIVE PROPERTIES COMPANY 2017-07-13 US disclosed
US-20170198129-A1 FLUOROPOLYMER COMPOSITION INCLUDING AT LEAST ONE OLIGOMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-07-13 US disclosed
US-4284485-A STABILIZED WITH A POLYALKYLPIPERIDINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed
US-4279720-A PHENYLGLYOXYLATE PHOTOINITIATOR WITH POLYALKYLPIPERIDINE STABILIZER CIBA-GEIGY CORPORATION (US) 1981-07-21 US disclosed
US-4276401-A N-Heterocyclic substituted acryloyl polymeric compounds CIBA-GEIGY CORPORATION (US) 1981-06-30 US disclosed
EP-0007059-B1 PHOTOCURABLE COMPOSITIONS CIBA-GEIGY AG (CH) 1981-04-15 EP disclosed
US-4256627-A COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
EP-0015230-A1 Stabilized organic Polymer comprising 2-(2-hydroxy-3,5-di-tert-octylphenyl)-2H-benzotriazole as a light-stabilizer CIBA-GEIGY AG (CH) 1980-09-03 EP disclosed
US-4210612-A LIGHT STABILIZERS FOR PLASTICS CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed
EP-0010518-A1 Acrylic copolymers bearing N-heterocyclic side rings, their use, and process for their preparation CIBA-GEIGY AG (CH) 1980-04-30 EP disclosed
EP-0007059-A1 Photocurable compositions CIBA-GEIGY AG (CH) 1980-01-23 EP disclosed
EP-0006564-A2 2-(3.5-disubstituted-2-hydroxyphenyl)-2H-benzotriazoles and stabilized compositions containing them CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170198119-A1 COPOLYMERS INCLUDING A TRIAZINE GROUP AND COMPOSITIONS INCLUDING THEM F12, XRCC5, TELO2 HDAC4 3423/4885HDAC6 2944/4885TEAD1 1716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.