Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404020 | 0.88 | LTA4H (0.44) | KMT2APTGS1PTGS2POLBALDH1A1 | |
| SCHEMBL5403560 | 0.87 | CYP1A2 (0.42) | KMT2AMEN1PTGS1PTGS2LMNA | |
| SCHEMBL5392936 | 0.84 | KMT2A (0.41) | KMT2AMEN1POLBLMNAALDH1A1 | |
| SCHEMBL5392572 | 0.83 | LTA4H (0.50) | KMT2AMEN1PTGS1PTGS2LMNA | |
| SCHEMBL5398626 | 0.81 | KCNH2 (0.42) | KMT2AMEN1POLBLMNAALDH1A1 | |
| SCHEMBL5406376 | 0.80 | MAPT (0.43) | PTGS1PTGS2 | |
| SCHEMBL5402972 | 0.80 | ACHE (0.43) | KMT2APTGS1PTGS2POLB | |
| SCHEMBL5402531 | 0.80 | LTA4H (0.45) | PTGS1PTGS2 | |
| SCHEMBL5418655 | 0.80 | PTGS1 (0.51) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL5407260 | 0.79 | CACNA1B (0.49) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169782-B2 | Aryl substituted thiazolidinones and the use thereof | EURO-CELTIQUE S.A. (LU) | 2007-01-30 | — | — | US | claimed |