SCHEMBL5418397

SCHEMBL5418397

C=CC(=O)NCOc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.51
TGM2 P21980 3/20 0.50
SMN1; SMN2 Q16637 4/20 0.48
RAB9A P51151 3/20 0.48
GLA P06280 1/20 0.48
GAA P10253 1/20 0.48
HTT P42858 1/20 0.48
ALOX15 P16050 1/20 0.46
RECQL P46063 2/20 0.45
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
HPGD P15428 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118050 0.83 RAB9A (0.66) THRBTGM2SMN1; SMN2RAB9ARECQL
SCHEMBL10363148 0.80 TGM2 (0.58) THRBTGM2SMN1; SMN2RAB9ARECQL
SCHEMBL10363121 0.79 TGM2 (0.60) THRBTGM2SMN1; SMN2RAB9ARECQL
SCHEMBL10363171 0.79 TGM2 (0.60) THRBTGM2SMN1; SMN2RAB9ARECQL
SCHEMBL10362509 0.79 TGM2 (0.60) THRBTGM2SMN1; SMN2RAB9ARECQL
SCHEMBL10362464 0.79 TGM2 (0.60) THRBTGM2SMN1; SMN2RAB9ARECQL
SCHEMBL10362406 0.79 TGM2 (0.60) THRBTGM2SMN1; SMN2RAB9ARECQL
SCHEMBL10363983 0.79 TGM2 (0.60) THRBTGM2SMN1; SMN2RAB9ARECQL
SCHEMBL10362422 0.79 TGM2 (0.60) THRBTGM2SMN1; SMN2RAB9ARECQL
SCHEMBL10362434 0.79 TGM2 (0.60) THRBTGM2SMN1; SMN2RAB9ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116360212-A Photoresist underlayer composition 罗门哈斯电子材料韩国有限公司 2023-06-30 CN disclosed
US-20230205087-A1 PHOTORESIST UNDERLAYER COMPOSITION DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-06-29 US disclosed
US-20230205087-A1 PHOTORESIST UNDERLAYER COMPOSITION DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-06-29 US disclosed
US-20210129184-A1 BRILLIANT PIGMENT-CONTAINING AQUEOUS BASE COAT COATING MATERIAL, AND METHOD FOR FORMING MULTILAYER FILM USING SAME KANSAI PAINT CO., LTD. (JP) 2021-05-06 US disclosed
US-20190039090-A1 BRILLIANT PIGMENT-CONTAINING AQUEOUS BASE COAT COATING MATERIAL, AND METHOD FOR FORMING MULTILAYER FILM USING SAME KANSAI PAINT CO., LTD. (JP) 2019-02-07 US disclosed
WO-2018202681-A1 USE OF DISUBSTITUTED BENZENES TO CONTROL INSECTICIDE-RESISTANT PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-11-08 WO disclosed
US-7247756-B2 1,4-disubstituted benzenes as insecticides BAYER CROPSCIENCE AG (DE) 2007-07-24 US disclosed
US-6753429-B2 FOR USE AS INSECTICIDES AGAINST A VARIETY OF INSECTS, INCLUDING LARVAE, SUCH AS TOBACCO BUDWORM FMC CORPORATION 2004-06-22 US disclosed
US-20030207894-A1 1,4-Disubstituted benzenes as insecticides BAYER CROPSCIENCE AG (DE) 2003-11-06 US disclosed
US-20020183342-A1 1,4-Disubstituted benzenes as insecticides BAYER CROPSCIENCE AG (DE) 2002-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207894-A1 1,4-Disubstituted benzenes as insecticides DDT, CYP1B1, CYP4B1 THRB 1238/4885TGM2 3339/4885SMN1; SMN2 1297/4885
US-20020183342-A1 1,4-Disubstituted benzenes as insecticides DDT, CYP1B1, CYP4B1 THRB 1238/4885TGM2 3339/4885SMN1; SMN2 1297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.