Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 7/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | HRH1 | P35367 | 6/20 | 0.46 |
| ▸ | CCR3 | P51677 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209950 | 0.94 | STS (0.55) | STSNAMPTGPR119 | |
| SCHEMBL2796623 | 0.81 | STS (0.67) | STSNAMPTGPR119 | |
| SCHEMBL14370267 | 0.81 | NAMPT (0.48) | STSNAMPTGPR119KDM4EALDH1A1 | |
| SCHEMBL7018366 | 0.80 | STS (0.57) | STSNAMPTGPR119 | |
| SCHEMBL16771053 | 0.80 | STS (0.69) | STSNAMPTGPR119KDM4E | |
| SCHEMBL5398564 | 0.79 | CCR3 (0.57) | HRH1CCR3 | |
| SCHEMBL4720822 | 0.79 | HRH1 (0.62) | GPR119HRH1CCR3KCNH2 | |
| SCHEMBL6880661 | 0.79 | NAMPT (0.48) | STSNAMPTGPR119 | |
| SCHEMBL18703633 | 0.78 | GPR119 (0.56) | STSNAMPTGPR119 | |
| SCHEMBL23546383 | 0.77 | GPR119 (0.60) | STSNAMPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179297-A1 | Chemical compounds | ASTRAZENECA AB, A SWEDEN CORPORATION | 2007-08-02 | — | — | US | disclosed |
| US-7238811-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2007-07-03 | — | — | US | disclosed |
| US-7179922-B2 | 4-Phenyloxypiperidionopiperidine compounds as antiinflammatory agents; autoimmune diseases; rheumatic diseases; cardiovascular disorders | ASTRAZENECA AB (SE) | 2007-02-20 | — | — | US | disclosed |
| US-20050171092-A1 | Chemical compounds | ASTRAZENECA AB, A SWEDEN CORPORATION | 2005-08-04 | — | — | US | disclosed |
| EP-1274701-B1 | [1,4']-BIPIPERIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2005-06-29 | — | — | EP | disclosed |
| US-6903115-B2 | Bipiperidine compounds | ASTRAZENECA AB (SE) | 2005-06-07 | — | — | US | disclosed |
| EP-1493743-A1 | Substituted bipiperidine intermediates and derivatives thereof | AstraZeneca AB (SE) | 2005-01-05 | — | — | EP | disclosed |
| US-20040014783-A1 | Chemical compounds | ASTRAZENECA AB, A SWEDEN CORPORATION | 2004-01-22 | — | — | US | disclosed |
| US-20040006080-A1 | Chemical compounds | ASTRAZENECA AB, A SWEDEN CORPORATION | 2004-01-08 | — | — | US | disclosed |
| US-6525070-B2 | For therapy of chemokine (such as CCR3) or H1 mediated disease state | ASTRAZENECA AB (SE) | 2003-02-25 | — | — | US | disclosed |
| US-20020077337-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2002-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077337-A1 | Chemical compounds | CCR3, CCR1, CCR4 | STS 3717/4885NAMPT 2296/4885GPR119 1917/4885 |
| US-20050171092-A1 | Chemical compounds | CCR3, CCR1, CCR4 | STS 3621/4885NAMPT 1953/4885GPR119 2100/4885 |
| US-20040006080-A1 | Chemical compounds | CCR3, CCR1, CCR4 | STS 3717/4885NAMPT 2296/4885GPR119 1917/4885 |
| US-20040014783-A1 | Chemical compounds | CCR3, CCR1, CCR4 | STS 3717/4885NAMPT 2296/4885GPR119 1917/4885 |
| US-20070179297-A1 | Chemical compounds | CCR3, CCR1, CCR4 | STS 3621/4885NAMPT 1953/4885GPR119 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.