SCHEMBL5419403

SCHEMBL5419403

Cc1c(Cc2cc(C=O)c(O)c(C)c2C)cc(C=O)c(O)c1C

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ERN1 O75460 12/20 0.52
▸ SRC P12931 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ PIM1 P11309 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30705750 0.78 ERN1 (0.65) ERN1PIM1
SCHEMBL5773682 0.77 ERN1 (0.58) ERN1PIM1
SCHEMBL8054676 0.77 ERN1 (0.46) ERN1LMNAMAPTPIM1
SCHEMBL14031706 0.77 ERN1 (0.58) ERN1MAPTPIM1
SCHEMBL210156 0.76 ERN1 (0.69) ERN1SRC
SCHEMBL31612188 0.76 ERN1 (0.69) ERN1SRC
SCHEMBL26857676 0.73 ERN1 (0.54) ERN1PIM1
SCHEMBL2921662 0.73 ERN1 (0.54) ERN1LMNAMAPT
SCHEMBL13623366 0.72 ERN1 (0.58) ERN1SRCPIM1
SCHEMBL1176032 0.72 SHBG (0.43) SRCLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120117968-A Process for preparing hydroxy-ortho-hydroxymethyl substituted methylene bridged substituted phenols and polyphenols containing multiple phenol units 天津久日半导体材料有限公司 2025-06-10 — — CN disclosed
US-20070232839-A1 NOVEL POLYNUCLEAR POLYPHENOL COMPOUND HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2007-10-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232839-A1 NOVEL POLYNUCLEAR POLYPHENOL COMPOUND TPR, PCNA, NCOA4 ERN1 3435/4885SRC 2322/4885LMNA 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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