⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841743 | 0.77 | — | — | |
| SCHEMBL14231348 | 0.73 | PKM (0.32) | — | |
| SCHEMBL6729102 | 0.71 | — | — | |
| SCHEMBL17612827 | 0.71 | — | — | |
| SCHEMBL3848292 | 0.69 | ADH1B (0.48) | — | |
| SCHEMBL2492609 | 0.69 | — | — | |
| SCHEMBL16965855 | 0.69 | — | — | |
| SCHEMBL5305975 | 0.69 | — | — | |
| SCHEMBL8009342 | 0.69 | — | — | |
| SCHEMBL8012550 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1699 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650827-B | Preparation method, intermediate compound and synthesis method for anthracycline derivatives | 戊言医药科技（上海）有限公司 | 2024-03-15 | — | — | CN | claimed |
| EP-3543355-B1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF P13K/AKT/MTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | TAIHO PHARMACEUTICAL CO LTD (JP) | 2020-12-23 | — | — | EP | claimed |
| EP-3012327-B1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF PI3K/AKT/mTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | TAIHO PHARMACEUTICAL CO LTD (JP) | 2020-12-16 | — | — | EP | claimed |
| CN-108530315-B | O-substituted hydroxylamine hydrochloride and preparation method thereof | 苏州昊帆生物股份有限公司 | 2020-11-24 | — | — | CN | claimed |
| EP-3543355-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF P13K/AKT/MTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | Taiho Pharmaceutical Co., Ltd. (JP) | 2019-09-25 | — | — | EP | claimed |
| US-10155990-B2 | Method for predicting therapeutic efficacy of PI3K/AKT/mTOR inhibitor on basis of PHLDA1 or PIK3C2B expression | Taiho Pharmaceuticals, Inc. (JP) | 2018-12-18 | — | — | US | claimed |
| EP-2868660-B1 | ANTITUMOR EFFECT POTENTIATOR COMPRISING AN IMIDAZOOXAZINE COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2017-12-27 | — | — | EP | claimed |
| US-9375434-B2 | Antitumor effect potentiator composed of imidazooxazine compound | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-06-28 | — | — | US | claimed |
| EP-3012327-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF PI3K/AKT/mTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | Taiho Pharmaceutical Co., Ltd. (JP) | 2016-04-27 | — | — | EP | claimed |
| US-20160102366-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF PI3K/AKT/mTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | TAIHO PHARMACEITUCAL CO., LTD. (JP) | 2016-04-14 | — | — | US | claimed |
| CN-1284068-A | Substituted phenyl uracils | BAYER AG (DE) | 2001-02-14 | — | — | CN | claimed |
| CN-1264377-A | Substituted pyrazoles as P38 kinase inhabitors | SEARLE & CO (US) | 2000-08-23 | — | — | CN | claimed |
| CN-1242003-A | Pesticidal 1-aryl and pyridylpyrazole derivatives | RHONE POULENC AGROCHIMIE (FR) | 2000-01-19 | — | — | CN | claimed |
| CN-1048240-C | Novel T-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 2000-01-12 | — | — | CN | claimed |
| EP-0763018-A2 | HETEROCYCLIC IMINO DERIVATIVES | BAYER AG (DE) | 1997-03-19 | — | — | EP | claimed |
| CN-1143360-A | Hydroxamic acid derivatives, process for their preparation and their use as fungicides | BAYER AG (DE) | 1997-02-19 | — | — | CN | claimed |
| WO-1995033717-A2 | HETEROCYCLIC IMINO DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-14 | — | — | WO | claimed |
| EP-0280240-B1 | Cephalosporin derivatives, process for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-09-14 | — | — | EP | claimed |
| CN-1072172-A | Novel 7-replacement-9-substituted-amino-6-demethyl-6-deoxidation tsiklomitsin | AMERICAN CYANAMID CO (US) | 1993-05-19 | — | — | CN | claimed |
| US-4160021-A | ANTIALLERGENS, ANTIHISTAMINES | SMITHKLINE CORPORATION (US) | 1979-07-03 | — | — | US | claimed |